Chemical Exposures at Work and Cardiovascular Morbidity Atherosclerosis, Ischemic Heart Disease, Hypertension, Cardiomyopathy and Arrhythmias

Relatively little systematic research has been directed towards the potential effects, either etiologic or aggravating, of industrial chemicals on cardiovascular diseases. While some evidence indicates that exposure to certain pesticides might affect lipoprotein metabolism in man, there is no consis...

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Veröffentlicht in:Scandinavian Journal of Work, Environment & Health Environment & Health, 1984-12, Vol.10 (6), p.381-388
Hauptverfasser: Kurppa, Kari, Hietanen, Eino, Klockars, Matti, Partinen, Markku, Rantanen, Jorma, Rönnemaa, Tapani, Viikari, Jorma
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container_end_page 388
container_issue 6
container_start_page 381
container_title Scandinavian Journal of Work, Environment & Health
container_volume 10
creator Kurppa, Kari
Hietanen, Eino
Klockars, Matti
Partinen, Markku
Rantanen, Jorma
Rönnemaa, Tapani
Viikari, Jorma
description Relatively little systematic research has been directed towards the potential effects, either etiologic or aggravating, of industrial chemicals on cardiovascular diseases. While some evidence indicates that exposure to certain pesticides might affect lipoprotein metabolism in man, there is no consistent documentation to support the view that atherosclerosis is caused in man by chemical exposures in industry. In this respect results from some animal studies are highly interesting, eg, exposure to some carcinogens, but the hypotheses presented have not yet been vigorously tested in man. Exposure to carbon monoxide is detrimental to the myocardium, especially in patients with ischémie heart disease, but there are no reliable data on elevated cardiac mortality due to carbon monoxide exposure in industrial populations. A few studies have reported arrhythmias or sudden deaths among workers exposed to solvents and organic nitrates. The effects of lead and cadmium upon human blood pressure have remained controversial, although the bulk of controlled epidemiologic studies suggests that they, if at all existent, are not strong.
doi_str_mv 10.5271/sjweh.2316
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identifier ISSN: 0355-3140
ispartof Scandinavian Journal of Work, Environment & Health, 1984-12, Vol.10 (6), p.381-388
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source MEDLINE; Jstor Complete Legacy; EZB-FREE-00999 freely available EZB journals
subjects Animals
Arrhythmias, Cardiac - chemically induced
Arsenic - toxicity
Arteriosclerosis - chemically induced
Atherosclerosis
Blood pressure
Cadmium
Cadmium - toxicity
Carbon Disulfide - toxicity
Carbon monoxide
Carbon Monoxide - toxicity
Cardiomyopathies - chemically induced
Chemical hazards
Cobalt - toxicity
Coronary Disease - chemically induced
Disulfides
Heart diseases
Humans
Hydrocarbons, Halogenated - toxicity
Hypertension
Hypertension - chemically induced
Lead
Lead - toxicity
Metals - toxicity
Mortality
Nitrates - toxicity
Occupational Diseases - chemically induced
Pesticides - toxicity
Polycyclic Compounds - toxicity
Risk
Solvents - toxicity
title Chemical Exposures at Work and Cardiovascular Morbidity Atherosclerosis, Ischemic Heart Disease, Hypertension, Cardiomyopathy and Arrhythmias
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