Red cell indices: differentiation between β-thalassemia trait and iron deficiency anemia and application to sickle cell disease and sickle cell thalassemia

In Tunisia, thalassemia and sickle cell disease (SS) represent the most prevalent monogenic hemoglobin disorders with 2.21% and 1.89% of carriers, respectively. This study aims to evaluate the diagnosis reliability of 12 red blood cell (RBC) indices in differentiation of β-thalassemia trait (β-TT) f...

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Veröffentlicht in:	Clinical chemistry and laboratory medicine 2013-08, Vol.51 (8), p.1595-1603
Hauptverfasser:	Sahli, Chaima A., Bibi, Amina, Ouali, Faida, Fredj, Sondess Hadj, Dakhlaoui, Boutheina, Othmani, Rym, Laaouini, Naouel, Jouini, Latifa, Ouenniche, Fekria, Siala, Hajer, Touhami, Imed, Becher, Mariem, Fattoum, Slaheddine, El Houda Toumi, Nour, Messaoud, Taieb
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anemia Anemia, Iron-Deficiency - blood Anemia, Sickle Cell - blood beta-Thalassemia - blood beta-Thalassemia - genetics Blood diseases Cell Differentiation Diagnosis Differential diagnosis Differentiation discrimination indice Erythrocyte Indices Erythrocytes Female Ferritins - blood Hemoglobin Humans Iron Iron deficiency iron deficiency anemia Male Mathematical analysis Middle Aged Mutation Nutrient deficiency Receptors, Transferrin - blood Reliability analysis ROC Curve Sequence Analysis, DNA Sickle cell disease sickle cell thalassemia Thalassemia Young Adult β-thalassemia trait
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