trans-Resveratrol in Gnetum gnemon Protects against Oxidative-Stress-Induced Endothelial Senescence

Gnetum gnemon is an arboreal dioecious plant that is cultivated in Indonesia. The seeds of this species mainly contain dimeric stilbenoid compounds [gnetin C (1), gnemonoside A (2), and gnemonoside D (3)] along with trans-resveratrol (4). trans-Resveratrol has been reported to have antiaging, antica...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2013-07, Vol.76 (7), p.1242-1247
Hauptverfasser:	Ota, Hidetaka, Akishita, Masahiro, Tani, Hiroko, Tatefuji, Tomoki, Ogawa, Sumito, Iijima, Katsuya, Eto, Masato, Shirasawa, Takuji, Ouchi, Yasuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Benzofurans - analysis Benzofurans - chemistry Benzofurans - isolation & purification Cellular Senescence - drug effects Diabetes Mellitus, Experimental Gnetum - chemistry Humans Hydrogen Peroxide - pharmacology Indonesia Mice Molecular Structure Nitric Oxide Synthase Type III - metabolism Oxidative Stress - drug effects Seeds - metabolism Sirtuin 1 - drug effects Stereoisomerism Stilbenes - analysis Stilbenes - chemistry Stilbenes - isolation & purification Stilbenes - pharmacology Umbilical Veins - cytology
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