TLR-4 polymorphisms and leukocyte TLR-4 expression in febrile UTI and renal scarring

Background In this study, we aimed to determine the relation of TLR-4 Asp299Gly and Thr399Ile polymorphisms and monocyte/neutrophil TLR-4 expression to febrile urinary tract infection (UTI) and renal scar development in children. Methods The study was performed in children with a history of febrile...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2013-09, Vol.28 (9), p.1827-1835
Hauptverfasser:	Bayram, Meral Torun, Soylu, Alper, Ateş, Halil, Kızıldağ, Sefa, Kavukçu, Salih
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymptomatic Bacterial infections Case studies Child Children Creatinine Diseases DNA - genetics Female Fever - complications Fever - metabolism Flow Cytometry Humans Immune system Kidney - pathology Kidney diseases Leukocytes Leukocytes - metabolism Lipopolysaccharides - pharmacology Male Medical research Medicine Medicine & Public Health Medicine, Experimental Monocytes - metabolism Nephrology Neutrophils Original Article Outpatient care facilities Pathogens Pediatrics Polymerase Chain Reaction Polymorphism Polymorphism, Genetic Polymorphism, Restriction Fragment Length - genetics Pyelonephritis - genetics Pyelonephritis - metabolism Scars Toll-Like Receptor 4 - biosynthesis Toll-Like Receptor 4 - genetics Urinary tract diseases Urinary tract infections Urinary Tract Infections - genetics Urinary Tract Infections - metabolism Urinary Tract Infections - pathology Urinary tract infections in children Urogenital system Urology
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