Flow cytometry and gene expression profiling of immune cells of the carotid plaque and peripheral blood

Abstract Objectives The relative contribution of the local vs. peripheral inflammation to the atherothrombotic processes is unknown. We compared the inflammatory status of the immune cells of the carotid plaque with similar cells in peripheral circulation of patients with advanced carotid disease (P...

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Veröffentlicht in:	Atherosclerosis 2013-08, Vol.229 (2), p.338-347
Hauptverfasser:	Sternberg, Zohara, Ghanim, Husam, Gillotti, Kristen M, Tario, Joseph D, Munschauer, Frederick, Curl, Richard, Noor, Sonya, Yu, Jihnhee, Ambrus, Julian L, Wallace, Paul, Dandona, Paresh
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over atherosclerosis B-Lymphocytes - cytology B-Lymphocytes - immunology Cardiovascular Carotid stenosis Carotid Stenosis - genetics Carotid Stenosis - immunology Carotid Stenosis - pathology Cell adhesion Cell Adhesion - immunology Cell surface markers disease course Female Flow Cytometry Gene expression Humans Immunomagnetic Separation Immunophenotyping inflammation Leukocytes, Mononuclear - cytology Leukocytes, Mononuclear - immunology Male messenger RNA Middle Aged monocytes Monocytes - cytology Monocytes - immunology Mononuclear cells patients reverse transcriptase polymerase chain reaction sorting T-lymphocytes T-Lymphocytes - cytology T-Lymphocytes - immunology Thrombosis Thrombosis - genetics Thrombosis - immunology Thrombosis - pathology Transcriptome - immunology transforming growth factor beta tumor necrosis factor-alpha Vasculitis - genetics Vasculitis - immunology Vasculitis - pathology
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