Development of a transdermal Salmonella challenge model in calves
Recent investigations have found that Salmonella can be routinely recovered from peripheral lymph nodes (PLNs) of cattle presented for harvest. When contained within the PLNs, this foodborne pathogen is protected from currently used postharvest, inplant intervention strategies and, therefore, PLNs h...
Gespeichert in:
| Veröffentlicht in: | Journal of food protection 2013-07, Vol.76 (7), p.1255-1258 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1258 |
|---|---|
| container_issue | 7 |
| container_start_page | 1255 |
| container_title | Journal of food protection |
| container_volume | 76 |
| creator | Edrington, T. S Loneragan, G. H Hill, J Genovese, K. J He, H Callaway, T. R Anderson, R. C Brichta-Harhay, D. M Nisbet, D. J |
| description | Recent investigations have found that Salmonella can be routinely recovered from peripheral lymph nodes (PLNs) of cattle presented for harvest. When contained within the PLNs, this foodborne pathogen is protected from currently used postharvest, inplant intervention strategies and, therefore, PLNs harboring Salmonella may be a potential contaminant of ground beef. The objective of this work was to develop a challenge model that effectively and repeatedly results in Salmonella-positive PLNs. A 10-lancet skin-allergy instrument was inoculated with Salmonella, and calves were inoculated intra- and/or transdermally by applying the device over various ventral regions of the skin. Salmonella was successfully and predictably recovered from regionspecific PLNs up to 8 days postchallenge. Furthermore, serotypes inoculated within specific regions were only recovered from the PLNs draining those regions. This model provides a method to predictably infect PLNs with Salmonella. Further, this model makes it possible to determine the duration of infection and to evaluate candidate interventions that may shorten the duration of infection. |
| doi_str_mv | 10.4315/0362-028X.JFP-12-317 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1412519620</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1412519620</sourcerecordid><originalsourceid>FETCH-LOGICAL-c449t-e9a5d5e75257ca976b4676a35074282bb516e7d7ab81e6bb8a4fbdb621c212d23</originalsourceid><addsrcrecordid>eNpd0N9rFDEQwPEgij2r_4HoghR82ZqZ_No8ltpqS6FCLfgWkt3ZeiW7uSZ3hf735rizgk95-cww-TL2HvixFKC-cKGx5dj9Or48_9ECtgLMC7YAK2VruTUv2eKZHLA3pdxzztGifs0OUHRCdhwX7OQrPVJMq4nmdZPGxjfr7OcyUJ58bG58nNJMMfqm_-1jpPmOmikNFJvl3PQ-PlJ5y16NPhZ6t38P2e352c_T7-3V9beL05OrtpfSrluyXg2KjEJlem-NDlIb7YXiRmKHISjQZAbjQwekQ-i8HMMQNEKPgAOKQ_Z5t3eV08OGytpNy9Jvb5spbYoDCajAauSVfvqP3qdNnut1DkSHpn5dmarkTvU5lZJpdKu8nHx-csDdNrHb9nPbfq4mdoCuJq5jH_bLN2Gi4Xnob9MKjvbAl5porD37ZfnnjLRWKaju486NPjl_l6u5vUEOknMwtuNW_AGEOovh</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1382748057</pqid></control><display><type>article</type><title>Development of a transdermal Salmonella challenge model in calves</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>ProQuest Central UK/Ireland</source><source>Alma/SFX Local Collection</source><creator>Edrington, T. S ; Loneragan, G. H ; Hill, J ; Genovese, K. J ; He, H ; Callaway, T. R ; Anderson, R. C ; Brichta-Harhay, D. M ; Nisbet, D. J</creator><creatorcontrib>Edrington, T. S ; Loneragan, G. H ; Hill, J ; Genovese, K. J ; He, H ; Callaway, T. R ; Anderson, R. C ; Brichta-Harhay, D. M ; Nisbet, D. J</creatorcontrib><description>Recent investigations have found that Salmonella can be routinely recovered from peripheral lymph nodes (PLNs) of cattle presented for harvest. When contained within the PLNs, this foodborne pathogen is protected from currently used postharvest, inplant intervention strategies and, therefore, PLNs harboring Salmonella may be a potential contaminant of ground beef. The objective of this work was to develop a challenge model that effectively and repeatedly results in Salmonella-positive PLNs. A 10-lancet skin-allergy instrument was inoculated with Salmonella, and calves were inoculated intra- and/or transdermally by applying the device over various ventral regions of the skin. Salmonella was successfully and predictably recovered from regionspecific PLNs up to 8 days postchallenge. Furthermore, serotypes inoculated within specific regions were only recovered from the PLNs draining those regions. This model provides a method to predictably infect PLNs with Salmonella. Further, this model makes it possible to determine the duration of infection and to evaluate candidate interventions that may shorten the duration of infection.</description><identifier>ISSN: 0362-028X</identifier><identifier>EISSN: 1944-9097</identifier><identifier>DOI: 10.4315/0362-028X.JFP-12-317</identifier><identifier>PMID: 23834802</identifier><identifier>CODEN: JFPRDR</identifier><language>eng</language><publisher>Des Moines, IA: International Association for Food Protection</publisher><subject>Allergies ; Animals ; Beef ; Biological and medical sciences ; calves ; Cattle ; Cattle - microbiology ; Colony Count, Microbial ; Contaminants ; Food contamination & poisoning ; Food Contamination - analysis ; Food Contamination - prevention & control ; Food industries ; Food Microbiology ; food pathogens ; Food safety ; Fundamental and applied biological sciences. Psychology ; Humans ; Infections ; Laboratories ; Lymph nodes ; Lymph Nodes - microbiology ; Lymphatic system ; Meat Products - microbiology ; Models, Animal ; Pathogens ; Prevalence ; Salmonella ; Salmonella - isolation & purification ; salmonellosis ; serotypes ; Skin ; transdermal application</subject><ispartof>Journal of food protection, 2013-07, Vol.76 (7), p.1255-1258</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright Allen Press Publishing Services Jul 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c449t-e9a5d5e75257ca976b4676a35074282bb516e7d7ab81e6bb8a4fbdb621c212d23</citedby><cites>FETCH-LOGICAL-c449t-e9a5d5e75257ca976b4676a35074282bb516e7d7ab81e6bb8a4fbdb621c212d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1382748057?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27499551$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23834802$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Edrington, T. S</creatorcontrib><creatorcontrib>Loneragan, G. H</creatorcontrib><creatorcontrib>Hill, J</creatorcontrib><creatorcontrib>Genovese, K. J</creatorcontrib><creatorcontrib>He, H</creatorcontrib><creatorcontrib>Callaway, T. R</creatorcontrib><creatorcontrib>Anderson, R. C</creatorcontrib><creatorcontrib>Brichta-Harhay, D. M</creatorcontrib><creatorcontrib>Nisbet, D. J</creatorcontrib><title>Development of a transdermal Salmonella challenge model in calves</title><title>Journal of food protection</title><addtitle>J Food Prot</addtitle><description>Recent investigations have found that Salmonella can be routinely recovered from peripheral lymph nodes (PLNs) of cattle presented for harvest. When contained within the PLNs, this foodborne pathogen is protected from currently used postharvest, inplant intervention strategies and, therefore, PLNs harboring Salmonella may be a potential contaminant of ground beef. The objective of this work was to develop a challenge model that effectively and repeatedly results in Salmonella-positive PLNs. A 10-lancet skin-allergy instrument was inoculated with Salmonella, and calves were inoculated intra- and/or transdermally by applying the device over various ventral regions of the skin. Salmonella was successfully and predictably recovered from regionspecific PLNs up to 8 days postchallenge. Furthermore, serotypes inoculated within specific regions were only recovered from the PLNs draining those regions. This model provides a method to predictably infect PLNs with Salmonella. Further, this model makes it possible to determine the duration of infection and to evaluate candidate interventions that may shorten the duration of infection.</description><subject>Allergies</subject><subject>Animals</subject><subject>Beef</subject><subject>Biological and medical sciences</subject><subject>calves</subject><subject>Cattle</subject><subject>Cattle - microbiology</subject><subject>Colony Count, Microbial</subject><subject>Contaminants</subject><subject>Food contamination & poisoning</subject><subject>Food Contamination - analysis</subject><subject>Food Contamination - prevention & control</subject><subject>Food industries</subject><subject>Food Microbiology</subject><subject>food pathogens</subject><subject>Food safety</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Infections</subject><subject>Laboratories</subject><subject>Lymph nodes</subject><subject>Lymph Nodes - microbiology</subject><subject>Lymphatic system</subject><subject>Meat Products - microbiology</subject><subject>Models, Animal</subject><subject>Pathogens</subject><subject>Prevalence</subject><subject>Salmonella</subject><subject>Salmonella - isolation & purification</subject><subject>salmonellosis</subject><subject>serotypes</subject><subject>Skin</subject><subject>transdermal application</subject><issn>0362-028X</issn><issn>1944-9097</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpd0N9rFDEQwPEgij2r_4HoghR82ZqZ_No8ltpqS6FCLfgWkt3ZeiW7uSZ3hf735rizgk95-cww-TL2HvixFKC-cKGx5dj9Or48_9ECtgLMC7YAK2VruTUv2eKZHLA3pdxzztGifs0OUHRCdhwX7OQrPVJMq4nmdZPGxjfr7OcyUJ58bG58nNJMMfqm_-1jpPmOmikNFJvl3PQ-PlJ5y16NPhZ6t38P2e352c_T7-3V9beL05OrtpfSrluyXg2KjEJlem-NDlIb7YXiRmKHISjQZAbjQwekQ-i8HMMQNEKPgAOKQ_Z5t3eV08OGytpNy9Jvb5spbYoDCajAauSVfvqP3qdNnut1DkSHpn5dmarkTvU5lZJpdKu8nHx-csDdNrHb9nPbfq4mdoCuJq5jH_bLN2Gi4Xnob9MKjvbAl5porD37ZfnnjLRWKaju486NPjl_l6u5vUEOknMwtuNW_AGEOovh</recordid><startdate>20130701</startdate><enddate>20130701</enddate><creator>Edrington, T. S</creator><creator>Loneragan, G. H</creator><creator>Hill, J</creator><creator>Genovese, K. J</creator><creator>He, H</creator><creator>Callaway, T. R</creator><creator>Anderson, R. C</creator><creator>Brichta-Harhay, D. M</creator><creator>Nisbet, D. J</creator><general>International Association for Food Protection</general><general>Elsevier Limited</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RQ</scope><scope>7WY</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>883</scope><scope>88E</scope><scope>88I</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>M0F</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PATMY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>7QL</scope><scope>C1K</scope></search><sort><creationdate>20130701</creationdate><title>Development of a transdermal Salmonella challenge model in calves</title><author>Edrington, T. S ; Loneragan, G. H ; Hill, J ; Genovese, K. J ; He, H ; Callaway, T. R ; Anderson, R. C ; Brichta-Harhay, D. M ; Nisbet, D. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c449t-e9a5d5e75257ca976b4676a35074282bb516e7d7ab81e6bb8a4fbdb621c212d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Allergies</topic><topic>Animals</topic><topic>Beef</topic><topic>Biological and medical sciences</topic><topic>calves</topic><topic>Cattle</topic><topic>Cattle - microbiology</topic><topic>Colony Count, Microbial</topic><topic>Contaminants</topic><topic>Food contamination & poisoning</topic><topic>Food Contamination - analysis</topic><topic>Food Contamination - prevention & control</topic><topic>Food industries</topic><topic>Food Microbiology</topic><topic>food pathogens</topic><topic>Food safety</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Infections</topic><topic>Laboratories</topic><topic>Lymph nodes</topic><topic>Lymph Nodes - microbiology</topic><topic>Lymphatic system</topic><topic>Meat Products - microbiology</topic><topic>Models, Animal</topic><topic>Pathogens</topic><topic>Prevalence</topic><topic>Salmonella</topic><topic>Salmonella - isolation & purification</topic><topic>salmonellosis</topic><topic>serotypes</topic><topic>Skin</topic><topic>transdermal application</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Edrington, T. S</creatorcontrib><creatorcontrib>Loneragan, G. H</creatorcontrib><creatorcontrib>Hill, J</creatorcontrib><creatorcontrib>Genovese, K. J</creatorcontrib><creatorcontrib>He, H</creatorcontrib><creatorcontrib>Callaway, T. R</creatorcontrib><creatorcontrib>Anderson, R. C</creatorcontrib><creatorcontrib>Brichta-Harhay, D. M</creatorcontrib><creatorcontrib>Nisbet, D. J</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Career & Technical Education Database</collection><collection>Access via ABI/INFORM (ProQuest)</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Trade & Industry (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Trade & Industry</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Environmental Science Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of food protection</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Edrington, T. S</au><au>Loneragan, G. H</au><au>Hill, J</au><au>Genovese, K. J</au><au>He, H</au><au>Callaway, T. R</au><au>Anderson, R. C</au><au>Brichta-Harhay, D. M</au><au>Nisbet, D. J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of a transdermal Salmonella challenge model in calves</atitle><jtitle>Journal of food protection</jtitle><addtitle>J Food Prot</addtitle><date>2013-07-01</date><risdate>2013</risdate><volume>76</volume><issue>7</issue><spage>1255</spage><epage>1258</epage><pages>1255-1258</pages><issn>0362-028X</issn><eissn>1944-9097</eissn><coden>JFPRDR</coden><abstract>Recent investigations have found that Salmonella can be routinely recovered from peripheral lymph nodes (PLNs) of cattle presented for harvest. When contained within the PLNs, this foodborne pathogen is protected from currently used postharvest, inplant intervention strategies and, therefore, PLNs harboring Salmonella may be a potential contaminant of ground beef. The objective of this work was to develop a challenge model that effectively and repeatedly results in Salmonella-positive PLNs. A 10-lancet skin-allergy instrument was inoculated with Salmonella, and calves were inoculated intra- and/or transdermally by applying the device over various ventral regions of the skin. Salmonella was successfully and predictably recovered from regionspecific PLNs up to 8 days postchallenge. Furthermore, serotypes inoculated within specific regions were only recovered from the PLNs draining those regions. This model provides a method to predictably infect PLNs with Salmonella. Further, this model makes it possible to determine the duration of infection and to evaluate candidate interventions that may shorten the duration of infection.</abstract><cop>Des Moines, IA</cop><pub>International Association for Food Protection</pub><pmid>23834802</pmid><doi>10.4315/0362-028X.JFP-12-317</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0362-028X |
| ispartof | Journal of food protection, 2013-07, Vol.76 (7), p.1255-1258 |
| issn | 0362-028X 1944-9097 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1412519620 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; Alma/SFX Local Collection |
| subjects | Allergies Animals Beef Biological and medical sciences calves Cattle Cattle - microbiology Colony Count, Microbial Contaminants Food contamination & poisoning Food Contamination - analysis Food Contamination - prevention & control Food industries Food Microbiology food pathogens Food safety Fundamental and applied biological sciences. Psychology Humans Infections Laboratories Lymph nodes Lymph Nodes - microbiology Lymphatic system Meat Products - microbiology Models, Animal Pathogens Prevalence Salmonella Salmonella - isolation & purification salmonellosis serotypes Skin transdermal application |
| title | Development of a transdermal Salmonella challenge model in calves |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T11%3A11%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20of%20a%20transdermal%20Salmonella%20challenge%20model%20in%20calves&rft.jtitle=Journal%20of%20food%20protection&rft.au=Edrington,%20T.%20S&rft.date=2013-07-01&rft.volume=76&rft.issue=7&rft.spage=1255&rft.epage=1258&rft.pages=1255-1258&rft.issn=0362-028X&rft.eissn=1944-9097&rft.coden=JFPRDR&rft_id=info:doi/10.4315/0362-028X.JFP-12-317&rft_dat=%3Cproquest_cross%3E1412519620%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1382748057&rft_id=info:pmid/23834802&rfr_iscdi=true |