Vacuolar protein sorting 4B, an ATPase protein positively regulates the progression of NSCLC via promoting cell division

Vacuolar protein sorting 4B (VPS4B), a member of ATPase family proteins, plays a crucial role in lysosome-dependent degradation. Recently, it was found that VPS4B could negatively regulate breast cancer progression through promoting lysosomal-dependent degradation for EGFR. Nevertheless, other studi...

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Veröffentlicht in:	Molecular and cellular biochemistry 2013-09, Vol.381 (1-2), p.163-171
Hauptverfasser:	Liu, Yifei, Lv, Liting, Xue, Qun, Wan, Chunhua, Ni, Tingting, Chen, Buyou, Liu, Yanhua, Zhou, Yiqun, Ni, Runzhou, Mao, Guoxin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Adenosine Triphosphatases - metabolism Adult Aged ATPases Associated with Diverse Cellular Activities Biochemistry Biomedical and Life Sciences Carcinoma, Non-Small-Cell Lung - enzymology Carcinoma, Non-Small-Cell Lung - pathology Cardiology Cell Cycle Cell Division Cell growth Cell Line, Tumor Cell Proliferation Disease Progression Endosomal Sorting Complexes Required for Transport - metabolism Female Gene expression Gene Knockdown Techniques Humans Immunohistochemistry Ki-67 Antigen - metabolism Life Sciences Lung cancer Lung cancer, Non-small cell Lung Neoplasms - enzymology Lung Neoplasms - pathology Male Medical Biochemistry Middle Aged Oncology Proportional Hazards Models Proteins Survival Analysis
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