ATP-Binding Cassette B10 Regulates Early Steps of Heme Synthesis

RATIONALE:Heme plays a critical role in gas exchange, mitochondrial energy production, and antioxidant defense in cardiovascular system. The mitochondrial transporter ATP-binding cassette (ABC) B10 has been suggested to export heme out of the mitochondria and is required for normal hemoglobinization...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Circulation research 2013-07, Vol.113 (3), p.279-287
Hauptverfasser:	Bayeva, Marina, Khechaduri, Arineh, Wu, Rongxue, Burke, Michael A, Wasserstrom, J Andrew, Singh, Neha, Liesa, Marc, Shirihai, Orian S, Langer, Nathaniel B, Paw, Barry H, Ardehali, Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP-Binding Cassette Transporters - physiology Cells, Cultured Heme - biosynthesis Heme - genetics Humans Mice Mice, Inbred C57BL Mitochondria, Heart - physiology Myocytes, Cardiac - physiology Rats
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!