Renal function and I alpha -hydroxyvitamin D sub(3) in rabbits with normal renal function and renal insufficiency

Renal function and I alpha -hydroxyvitamin D sub(3) in rabbits with normal renal function and renal insufficiency

The effect of I alpha -hydroxyvitamin D sub(3) (1 alpha OHD sub(3)) on the renal clearance of creatinine was investigated in groups of rabbits with stable renal insufficiency and normal controls. Then, I alpha OHD sub(3), 0.02 mu g/kg BW/day, was administered orally and urine was collected during th...

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Veröffentlicht in:Scandinavian journal of urology and nephrology 1983-01, Vol.17 (3), p.373-376
1. Verfasser: Tvedegaard, E
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container_title Scandinavian journal of urology and nephrology
container_volume 17
creator Tvedegaard, E
description The effect of I alpha -hydroxyvitamin D sub(3) (1 alpha OHD sub(3)) on the renal clearance of creatinine was investigated in groups of rabbits with stable renal insufficiency and normal controls. Then, I alpha OHD sub(3), 0.02 mu g/kg BW/day, was administered orally and urine was collected during the next two weeks. The treatment had no significant effect on the serum concentrations of calcium and phosphate in either group. Creatinine clearance decreased significantly in both groups during the I alpha OHD, treatment mainly due to a decreased urinary excretion of creatinine.
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source Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete
title Renal function and I alpha -hydroxyvitamin D sub(3) in rabbits with normal renal function and renal insufficiency
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