Degenerative changes in the developing nervous system as a result of in utero exposure to methylmercury

Tissue samples from the cerebral and cerebellar cortex of neonatal rats which had been prenatally exposed to low doses of methylmercury were examined by electron microscopy. Although all these neonates appeared to be physically normal, ultrastructural examination revealed various degenerative change...

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Veröffentlicht in:	Environ. Res.; (United States) 1977-12, Vol.14 (3), p.414-423
Hauptverfasser:	Chang, Louis W., Reuhl, Kenneth R., Lee, George W.
Format:	Artikel
Sprache:	eng
Schlagworte:	550900 - Pathology 560305 - Chemicals Metabolism & Toxicology- Vertebrates- (-1987) ANIMALS BASIC BIOLOGICAL SCIENCES BIOLOGICAL EFFECTS BODY BRAIN Brain - drug effects Brain - pathology CELL CONSTITUENTS CELL NUCLEI CENTRAL NERVOUS SYSTEM Cerebellar Cortex - ultrastructure Cerebral Cortex - ultrastructure DISEASES ELECTRON MICROSCOPY ENDOTHELIUM Female FEMALE GENITALS Fetus - drug effects MAMMALS Maternal-Fetal Exchange MEMBRANES METHYLMERCURY Methylmercury Compounds - toxicity MICROSCOPY MORPHOLOGICAL CHANGES NEONATES NERVOUS SYSTEM ORGANIC COMPOUNDS ORGANIC MERCURY COMPOUNDS ORGANS PATHOLOGICAL CHANGES PREGNANCY RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RATS RODENTS TISSUES ULTRASTRUCTURAL CHANGES UTERUS VERTEBRATES
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