A Death from Fentanyl Overdose
A case of death from self-injection of fentanyl and a method for its detection in autopsy specimens are reported. Fentanyl was measured by extraction of biological samples with ethyl acetate, partitioning into 0.1N HCl, then reextracting into ethyl acetate after alkalinization of the acid phase. Aft...
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| Veröffentlicht in: | Journal of analytical toxicology 1984-11, Vol.8 (6), p.288-289 |
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| container_end_page | 289 |
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| container_issue | 6 |
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| container_title | Journal of analytical toxicology |
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| creator | Garriott, James C. Rodriguez, Robert Di Maio, Vincent J.M. |
| description | A case of death from self-injection of fentanyl and a method for its detection in autopsy specimens are reported. Fentanyl was measured by extraction of biological samples with ethyl acetate, partitioning into 0.1N HCl, then reextracting into ethyl acetate after alkalinization of the acid phase. After reducing to a residue, the fentanyl was measured by selective ion monitoring gas chromatography/mase spectrometry. Concentrations of 4.8, 6.3, and 4.7 µg/L were found in blood, urine, and bile, respectively. |
| doi_str_mv | 10.1093/jat/8.6.288 |
| format | Article |
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Fentanyl was measured by extraction of biological samples with ethyl acetate, partitioning into 0.1N HCl, then reextracting into ethyl acetate after alkalinization of the acid phase. After reducing to a residue, the fentanyl was measured by selective ion monitoring gas chromatography/mase spectrometry. Concentrations of 4.8, 6.3, and 4.7 µg/L were found in blood, urine, and bile, respectively.</description><identifier>ISSN: 0146-4760</identifier><identifier>EISSN: 1945-2403</identifier><identifier>DOI: 10.1093/jat/8.6.288</identifier><identifier>PMID: 6521439</identifier><identifier>CODEN: JATOD3</identifier><language>eng</language><publisher>Niles, IL: Oxford University Press</publisher><subject>Adult ; Biological and medical sciences ; Drug intoxications. Doping ; Fentanyl - analysis ; Fentanyl - poisoning ; Gas Chromatography-Mass Spectrometry ; Humans ; Male ; Medical sciences ; Pharmacology. 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Fentanyl was measured by extraction of biological samples with ethyl acetate, partitioning into 0.1N HCl, then reextracting into ethyl acetate after alkalinization of the acid phase. After reducing to a residue, the fentanyl was measured by selective ion monitoring gas chromatography/mase spectrometry. Concentrations of 4.8, 6.3, and 4.7 µg/L were found in blood, urine, and bile, respectively.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Drug intoxications. Doping</subject><subject>Fentanyl - analysis</subject><subject>Fentanyl - poisoning</subject><subject>Gas Chromatography-Mass Spectrometry</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology. 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Doping</topic><topic>Fentanyl - analysis</topic><topic>Fentanyl - poisoning</topic><topic>Gas Chromatography-Mass Spectrometry</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garriott, James C.</creatorcontrib><creatorcontrib>Rodriguez, Robert</creatorcontrib><creatorcontrib>Di Maio, Vincent J.M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of analytical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garriott, James C.</au><au>Rodriguez, Robert</au><au>Di Maio, Vincent J.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Death from Fentanyl Overdose</atitle><jtitle>Journal of analytical toxicology</jtitle><addtitle>Journal of Analytical Toxicology</addtitle><date>1984-11</date><risdate>1984</risdate><volume>8</volume><issue>6</issue><spage>288</spage><epage>289</epage><pages>288-289</pages><issn>0146-4760</issn><eissn>1945-2403</eissn><coden>JATOD3</coden><abstract>A case of death from self-injection of fentanyl and a method for its detection in autopsy specimens are reported. Fentanyl was measured by extraction of biological samples with ethyl acetate, partitioning into 0.1N HCl, then reextracting into ethyl acetate after alkalinization of the acid phase. After reducing to a residue, the fentanyl was measured by selective ion monitoring gas chromatography/mase spectrometry. Concentrations of 4.8, 6.3, and 4.7 µg/L were found in blood, urine, and bile, respectively.</abstract><cop>Niles, IL</cop><pub>Oxford University Press</pub><pmid>6521439</pmid><doi>10.1093/jat/8.6.288</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0146-4760 |
| ispartof | Journal of analytical toxicology, 1984-11, Vol.8 (6), p.288-289 |
| issn | 0146-4760 1945-2403 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_14048313 |
| source | MEDLINE; Oxford Journals A-Z Collection; Alma/SFX Local Collection |
| subjects | Adult Biological and medical sciences Drug intoxications. Doping Fentanyl - analysis Fentanyl - poisoning Gas Chromatography-Mass Spectrometry Humans Male Medical sciences Pharmacology. Drug treatments |
| title | A Death from Fentanyl Overdose |
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