Seizures produced by pilocarpine in mice: A behavioral, electroencephalographic and morphological analysis

Increasing doses of pilocarpine, 100–400 mg/kg, were given intraperitoneally to mice and the resulting behavioral, electroencephalographic and neuropathological alterations were studied. No behavioral phenomena were observed in mice treated with the lowest dose of pilocarpine. Occasional tremor and...

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Veröffentlicht in:	Brain research 1984-11, Vol.321 (2), p.237-253
Hauptverfasser:	Turski, Waldemar A., Cavalheiro, Esper A., Bortolotto, Zuner A., Mello, Luiz M., Schwarz, Michael, Turski, Lechosław
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain - pathology brain damage Brain Diseases - chemically induced Cholinergic Fibers - physiology diazepam Disease Models, Animal Electroencephalography Limbic System - drug effects Male Medical sciences Mice mouse Nervous system involvement in other diseases. Miscellaneous Neurology pilocarpine Pilocarpine - antagonists & inhibitors Pilocarpine - toxicity scopolamine seizures Seizures - chemically induced Seizures - pathology Seizures - physiopathology temporal lobe epilepsy
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