Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors
Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring ef...
Gespeichert in:
| Veröffentlicht in: | Archives of environmental contamination and toxicology 1975, Vol.3 (1), p.1-21 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 21 |
|---|---|
| container_issue | 1 |
| container_start_page | 1 |
| container_title | Archives of environmental contamination and toxicology |
| container_volume | 3 |
| creator | Ludke, J L Hill, E F Dieter, M P |
| description | Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring effects of selected ChE inhibitors in birds. Brain ChE inhibition exceeding 20 percent indicated exposure, and inhibition greater than 50 percent was sufficient for diagnosing cause of death. Individuals that died from dietary exposure to parathion-1 or carbofuran had brain ChE activities below 55 percent of normal; although individuals could survive with brain ChE activity lower than 50 percent. Problems associated with collection, storage, and analysis of tissues for ChE activity are discussed. |
| doi_str_mv | 10.1007/BF02221128 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_14045545</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>14045545</sourcerecordid><originalsourceid>FETCH-LOGICAL-c228t-21eec7f4b3fcd32e3016a4391e9f5d1751be41a8a6d3437706e694af63d8f4da3</originalsourceid><addsrcrecordid>eNpFkE1LAzEQhoMotVYv3oU9iQqrM0n266ilVaEgiJ6X7GZiI7ubmmwP_fdGWvA0vMwzL8zD2CXCPQIUD09L4Jwj8vKITVEKnkIB4phNASpIpZB4ys5C-AaISCknbIIooOTVlL3P166zA4WRvAqU3MzXi9vEU9i4IUY16Bg6NZJOeudH1dlxl6jeDV9JY70OiYmbeJPYYW0bOzofztmJUV2gi8Ocsc_l4mP-kq7enl_nj6u05bwcU45EbWFkI0yrBScBmCspKqTKZBqLDBuSqEqVayFFUUBOeSWVyYUujdRKzNj1vnfj3c82flD3NrTUdWogtw01SpBZJrMI3u3B1rsQPJl6422v_K5GqP8E1v8CI3x1aN02Pel_dG9M_ALSjmn4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14045545</pqid></control><display><type>article</type><title>Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Ludke, J L ; Hill, E F ; Dieter, M P</creator><creatorcontrib>Ludke, J L ; Hill, E F ; Dieter, M P</creatorcontrib><description>Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring effects of selected ChE inhibitors in birds. Brain ChE inhibition exceeding 20 percent indicated exposure, and inhibition greater than 50 percent was sufficient for diagnosing cause of death. Individuals that died from dietary exposure to parathion-1 or carbofuran had brain ChE activities below 55 percent of normal; although individuals could survive with brain ChE activity lower than 50 percent. Problems associated with collection, storage, and analysis of tissues for ChE activity are discussed.</description><identifier>ISSN: 0090-4341</identifier><identifier>EISSN: 1432-0703</identifier><identifier>DOI: 10.1007/BF02221128</identifier><identifier>PMID: 1130829</identifier><language>eng</language><publisher>United States</publisher><subject>Aging ; Animals ; Animals, Newborn ; Birds - metabolism ; Brain - enzymology ; Cholinesterase Inhibitors - pharmacology ; Cholinesterases - blood ; Cholinesterases - metabolism ; Ducks - metabolism ; Female ; Lethal Dose 50 ; Male ; Parathion - pharmacology ; Parathion - toxicity ; Quail - metabolism ; Time Factors</subject><ispartof>Archives of environmental contamination and toxicology, 1975, Vol.3 (1), p.1-21</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c228t-21eec7f4b3fcd32e3016a4391e9f5d1751be41a8a6d3437706e694af63d8f4da3</citedby><cites>FETCH-LOGICAL-c228t-21eec7f4b3fcd32e3016a4391e9f5d1751be41a8a6d3437706e694af63d8f4da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4009,27902,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1130829$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ludke, J L</creatorcontrib><creatorcontrib>Hill, E F</creatorcontrib><creatorcontrib>Dieter, M P</creatorcontrib><title>Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors</title><title>Archives of environmental contamination and toxicology</title><addtitle>Arch Environ Contam Toxicol</addtitle><description>Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring effects of selected ChE inhibitors in birds. Brain ChE inhibition exceeding 20 percent indicated exposure, and inhibition greater than 50 percent was sufficient for diagnosing cause of death. Individuals that died from dietary exposure to parathion-1 or carbofuran had brain ChE activities below 55 percent of normal; although individuals could survive with brain ChE activity lower than 50 percent. Problems associated with collection, storage, and analysis of tissues for ChE activity are discussed.</description><subject>Aging</subject><subject>Animals</subject><subject>Animals, Newborn</subject><subject>Birds - metabolism</subject><subject>Brain - enzymology</subject><subject>Cholinesterase Inhibitors - pharmacology</subject><subject>Cholinesterases - blood</subject><subject>Cholinesterases - metabolism</subject><subject>Ducks - metabolism</subject><subject>Female</subject><subject>Lethal Dose 50</subject><subject>Male</subject><subject>Parathion - pharmacology</subject><subject>Parathion - toxicity</subject><subject>Quail - metabolism</subject><subject>Time Factors</subject><issn>0090-4341</issn><issn>1432-0703</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LAzEQhoMotVYv3oU9iQqrM0n266ilVaEgiJ6X7GZiI7ubmmwP_fdGWvA0vMwzL8zD2CXCPQIUD09L4Jwj8vKITVEKnkIB4phNASpIpZB4ys5C-AaISCknbIIooOTVlL3P166zA4WRvAqU3MzXi9vEU9i4IUY16Bg6NZJOeudH1dlxl6jeDV9JY70OiYmbeJPYYW0bOzofztmJUV2gi8Ocsc_l4mP-kq7enl_nj6u05bwcU45EbWFkI0yrBScBmCspKqTKZBqLDBuSqEqVayFFUUBOeSWVyYUujdRKzNj1vnfj3c82flD3NrTUdWogtw01SpBZJrMI3u3B1rsQPJl6422v_K5GqP8E1v8CI3x1aN02Pel_dG9M_ALSjmn4</recordid><startdate>1975</startdate><enddate>1975</enddate><creator>Ludke, J L</creator><creator>Hill, E F</creator><creator>Dieter, M P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope></search><sort><creationdate>1975</creationdate><title>Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors</title><author>Ludke, J L ; Hill, E F ; Dieter, M P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c228t-21eec7f4b3fcd32e3016a4391e9f5d1751be41a8a6d3437706e694af63d8f4da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Aging</topic><topic>Animals</topic><topic>Animals, Newborn</topic><topic>Birds - metabolism</topic><topic>Brain - enzymology</topic><topic>Cholinesterase Inhibitors - pharmacology</topic><topic>Cholinesterases - blood</topic><topic>Cholinesterases - metabolism</topic><topic>Ducks - metabolism</topic><topic>Female</topic><topic>Lethal Dose 50</topic><topic>Male</topic><topic>Parathion - pharmacology</topic><topic>Parathion - toxicity</topic><topic>Quail - metabolism</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ludke, J L</creatorcontrib><creatorcontrib>Hill, E F</creatorcontrib><creatorcontrib>Dieter, M P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><jtitle>Archives of environmental contamination and toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ludke, J L</au><au>Hill, E F</au><au>Dieter, M P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors</atitle><jtitle>Archives of environmental contamination and toxicology</jtitle><addtitle>Arch Environ Contam Toxicol</addtitle><date>1975</date><risdate>1975</risdate><volume>3</volume><issue>1</issue><spage>1</spage><epage>21</epage><pages>1-21</pages><issn>0090-4341</issn><eissn>1432-0703</eissn><abstract>Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring effects of selected ChE inhibitors in birds. Brain ChE inhibition exceeding 20 percent indicated exposure, and inhibition greater than 50 percent was sufficient for diagnosing cause of death. Individuals that died from dietary exposure to parathion-1 or carbofuran had brain ChE activities below 55 percent of normal; although individuals could survive with brain ChE activity lower than 50 percent. Problems associated with collection, storage, and analysis of tissues for ChE activity are discussed.</abstract><cop>United States</cop><pmid>1130829</pmid><doi>10.1007/BF02221128</doi><tpages>21</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0090-4341 |
| ispartof | Archives of environmental contamination and toxicology, 1975, Vol.3 (1), p.1-21 |
| issn | 0090-4341 1432-0703 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_14045545 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Aging Animals Animals, Newborn Birds - metabolism Brain - enzymology Cholinesterase Inhibitors - pharmacology Cholinesterases - blood Cholinesterases - metabolism Ducks - metabolism Female Lethal Dose 50 Male Parathion - pharmacology Parathion - toxicity Quail - metabolism Time Factors |
| title | Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T04%3A39%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cholinesterase%20(ChE)%20response%20and%20related%20mortality%20among%20birds%20fed%20ChE%20inhibitors&rft.jtitle=Archives%20of%20environmental%20contamination%20and%20toxicology&rft.au=Ludke,%20J%20L&rft.date=1975&rft.volume=3&rft.issue=1&rft.spage=1&rft.epage=21&rft.pages=1-21&rft.issn=0090-4341&rft.eissn=1432-0703&rft_id=info:doi/10.1007/BF02221128&rft_dat=%3Cproquest_cross%3E14045545%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14045545&rft_id=info:pmid/1130829&rfr_iscdi=true |