Short-term toxicity of pentachlorophenol in rats

Pentachlorophenol (PCP) was fed to rats at dietary levels of 0, 25, 50 and 200 ppm for 12 weeks. Growth was decreased in the group of female rats fed 200 ppm. The treatment had no effect on food intake and behaviour. Liver weight was increased at the 50 and 200 ppm dose levels accompanied by an incr...

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Veröffentlicht in:	Toxicology (Amsterdam) 1974-06, Vol.2 (2), p.141-152
Hauptverfasser:	Knudsen, I., Verschuuren, H.G., Den Tonkelaar, Engelina M., Kroes, R., Helleman, P.F.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Alanine Transaminase - blood Alkaline Phosphatase - blood Aminopyrine N-Demethylase - blood Aniline Compounds Animals Behavior, Animal - drug effects Blood Glucose - analysis Blood Proteins - analysis Calcium - metabolism Female Glucose-6-Phosphatase - blood Hemoglobins - analysis Herbicides - toxicity Kidney - drug effects Liver - drug effects Male Microsomes, Liver - drug effects Microsomes, Liver - enzymology Mixed Function Oxygenases - blood Organ Size Pentachlorophenol - administration & dosage Pentachlorophenol - toxicity Phenols - toxicity Rats Time Factors
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