EFFECT OF NITROUS OXIDE ON HALOTHANE-INDUCED HEPATOTOXICITY IN HYPOXIC, ENZYME-INDUCED RATS

The degree of hepatotoxicity induced by halothane in hypoxic (14% inspired oxygen), enzyme-induced (phenobarbitone treatment for 10 days), male Sprague-Dawley rats was assessed by histological examination and analysis of serum aspartate aminotransferase (Asp. AT) concentrations. There was a signific...

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Veröffentlicht in:	British journal of anaesthesia : BJA 1984-05, Vol.56 (5), p.527-533
Hauptverfasser:	ROSS, J.A.S., MONK, S.J., DUFFY, S.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics. Neuromuscular blocking agents Animals Biological and medical sciences Disease Models, Animal Drug Synergism Halothane - toxicity Liver - drug effects Male Medical sciences Neuropharmacology Nitrous Oxide - pharmacology Oxygen - physiology Pharmacology. Drug treatments Phenobarbital - pharmacology Rats Rats, Inbred Strains
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