Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer
Background The choice of surgical strategy for patients with proximal gastric cancer is controversial. The purpose of this study was to assess the feasibility, safety, and surgical and functional outcomes of laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy...
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| Veröffentlicht in: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2013-07, Vol.16 (3), p.282-289 |
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| container_title | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association |
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| creator | Ahn, Sang-Hoon Lee, Ju Hee Park, Do Joong Kim, Hyung-Ho |
| description | Background
The choice of surgical strategy for patients with proximal gastric cancer is controversial. The purpose of this study was to assess the feasibility, safety, and surgical and functional outcomes of laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG).
Methods
Between June 2003 and December 2009, 131 patients with proximal gastric cancer underwent LAPG (
n
= 50) or LATG (
n
= 81) at Seoul National University Bundang Hospital. We reviewed their medical and surgical records from our prospectively collected gastric cancer database. The clinicopathologic characteristics and short-term, long-term, and functional outcomes were compared between the 2 groups.
Results
There were no significant differences in demographics, T-stage, N-stage, or survival between the 2 groups. The LAPG group had a shorter operative time and lower estimated blood loss than the LATG group. The early complication rates after the LAPG and LATG procedures were 24.0 and 17.3 %, respectively (
p
= 0.349). The incidence of reflux symptoms was significantly higher in the LAPG group (32.0 vs. 3.7 %,
p
|
| doi_str_mv | 10.1007/s10120-012-0178-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1401090640</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1401090640</sourcerecordid><originalsourceid>FETCH-LOGICAL-c489t-c49e544e0ae00c038ee2cfd37b937d9014e6f9cbf60db0669bba48fc02b7f39b3</originalsourceid><addsrcrecordid>eNp1kc9q3DAQxkVoaf71AXIpgl7Sg9uR7LWtY1japLDQHtKzkORRcLCtrSQnuw-Vd-wsm4SSpgeNBPp934z0MXYm4LMAaL4kAUJCQYVW0xabA3YkqrIuyhIWb57OUolDdpzSLYBYKFG_Y4dStlKIVh6xh2UY1yaa3N8hT3nutjx47oZ-6p0ZeJizCyMmbjHfI058MESH5MJ6W5iU-pSx4-sYNv1I-I1JOaLLYdzy89XFz8tP3Ezd66Ic8r-Ka1L4EF849o47MzmMp-ytN0PC94_7Cfv17ev18qpY_bj8vrxYFa5qVaaqcFFVCAYBHJQtonS-KxuryqZTICqsvXLW19BZqGtlrala70DaxpfKlifsfO9Lc_yeMWU99snhMJgJw5y0qECAgroCQj--QG_DHCeabkdR74b-nCixpxz9Q4ro9TrS--JWC9C7LPU-S01F77LUG9J8eHSe7Yjds-IpPALkHkh0Nd1g_Kv1f13_ABkmriI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1400387591</pqid></control><display><type>article</type><title>Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><source>EZB Electronic Journals Library</source><creator>Ahn, Sang-Hoon ; Lee, Ju Hee ; Park, Do Joong ; Kim, Hyung-Ho</creator><creatorcontrib>Ahn, Sang-Hoon ; Lee, Ju Hee ; Park, Do Joong ; Kim, Hyung-Ho</creatorcontrib><description>Background
The choice of surgical strategy for patients with proximal gastric cancer is controversial. The purpose of this study was to assess the feasibility, safety, and surgical and functional outcomes of laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG).
Methods
Between June 2003 and December 2009, 131 patients with proximal gastric cancer underwent LAPG (
n
= 50) or LATG (
n
= 81) at Seoul National University Bundang Hospital. We reviewed their medical and surgical records from our prospectively collected gastric cancer database. The clinicopathologic characteristics and short-term, long-term, and functional outcomes were compared between the 2 groups.
Results
There were no significant differences in demographics, T-stage, N-stage, or survival between the 2 groups. The LAPG group had a shorter operative time and lower estimated blood loss than the LATG group. The early complication rates after the LAPG and LATG procedures were 24.0 and 17.3 %, respectively (
p
= 0.349). The incidence of reflux symptoms was significantly higher in the LAPG group (32.0 vs. 3.7 %,
p
< 0.001). The parameters that reflected nutritional status were similar in the 2 groups.
Conclusion
LAPG is a feasible and acceptable method for treating proximal early gastric cancer in terms of surgical and oncologic safety. However, esophagogastrostomy after LAPG was associated with an increased risk of reflux symptoms. Antireflux procedures should be considered to prevent reflux symptoms after LAPG.</description><identifier>ISSN: 1436-3291</identifier><identifier>EISSN: 1436-3305</identifier><identifier>DOI: 10.1007/s10120-012-0178-x</identifier><identifier>PMID: 22821182</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Abdominal Surgery ; Aged ; Blood Loss, Surgical ; Cancer Research ; Clinical outcomes ; Databases, Factual ; Feasibility Studies ; Female ; Follow-Up Studies ; Gastrectomy - methods ; Gastric cancer ; Gastroenterology ; Gastroesophageal Reflux - epidemiology ; Gastroesophageal Reflux - etiology ; Gastroesophageal Reflux - prevention & control ; Humans ; Laparoscopy - methods ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Oncology ; Operative Time ; Original Article ; Republic of Korea ; Retrospective Studies ; Stomach Neoplasms - pathology ; Stomach Neoplasms - surgery ; Surgical Oncology ; Time Factors</subject><ispartof>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2013-07, Vol.16 (3), p.282-289</ispartof><rights>The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2012</rights><rights>The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c489t-c49e544e0ae00c038ee2cfd37b937d9014e6f9cbf60db0669bba48fc02b7f39b3</citedby><cites>FETCH-LOGICAL-c489t-c49e544e0ae00c038ee2cfd37b937d9014e6f9cbf60db0669bba48fc02b7f39b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10120-012-0178-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10120-012-0178-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22821182$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ahn, Sang-Hoon</creatorcontrib><creatorcontrib>Lee, Ju Hee</creatorcontrib><creatorcontrib>Park, Do Joong</creatorcontrib><creatorcontrib>Kim, Hyung-Ho</creatorcontrib><title>Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer</title><title>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</title><addtitle>Gastric Cancer</addtitle><addtitle>Gastric Cancer</addtitle><description>Background
The choice of surgical strategy for patients with proximal gastric cancer is controversial. The purpose of this study was to assess the feasibility, safety, and surgical and functional outcomes of laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG).
Methods
Between June 2003 and December 2009, 131 patients with proximal gastric cancer underwent LAPG (
n
= 50) or LATG (
n
= 81) at Seoul National University Bundang Hospital. We reviewed their medical and surgical records from our prospectively collected gastric cancer database. The clinicopathologic characteristics and short-term, long-term, and functional outcomes were compared between the 2 groups.
Results
There were no significant differences in demographics, T-stage, N-stage, or survival between the 2 groups. The LAPG group had a shorter operative time and lower estimated blood loss than the LATG group. The early complication rates after the LAPG and LATG procedures were 24.0 and 17.3 %, respectively (
p
= 0.349). The incidence of reflux symptoms was significantly higher in the LAPG group (32.0 vs. 3.7 %,
p
< 0.001). The parameters that reflected nutritional status were similar in the 2 groups.
Conclusion
LAPG is a feasible and acceptable method for treating proximal early gastric cancer in terms of surgical and oncologic safety. However, esophagogastrostomy after LAPG was associated with an increased risk of reflux symptoms. Antireflux procedures should be considered to prevent reflux symptoms after LAPG.</description><subject>Abdominal Surgery</subject><subject>Aged</subject><subject>Blood Loss, Surgical</subject><subject>Cancer Research</subject><subject>Clinical outcomes</subject><subject>Databases, Factual</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastrectomy - methods</subject><subject>Gastric cancer</subject><subject>Gastroenterology</subject><subject>Gastroesophageal Reflux - epidemiology</subject><subject>Gastroesophageal Reflux - etiology</subject><subject>Gastroesophageal Reflux - prevention & control</subject><subject>Humans</subject><subject>Laparoscopy - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Operative Time</subject><subject>Original Article</subject><subject>Republic of Korea</subject><subject>Retrospective Studies</subject><subject>Stomach Neoplasms - pathology</subject><subject>Stomach Neoplasms - surgery</subject><subject>Surgical Oncology</subject><subject>Time Factors</subject><issn>1436-3291</issn><issn>1436-3305</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kc9q3DAQxkVoaf71AXIpgl7Sg9uR7LWtY1japLDQHtKzkORRcLCtrSQnuw-Vd-wsm4SSpgeNBPp934z0MXYm4LMAaL4kAUJCQYVW0xabA3YkqrIuyhIWb57OUolDdpzSLYBYKFG_Y4dStlKIVh6xh2UY1yaa3N8hT3nutjx47oZ-6p0ZeJizCyMmbjHfI058MESH5MJ6W5iU-pSx4-sYNv1I-I1JOaLLYdzy89XFz8tP3Ezd66Ic8r-Ka1L4EF849o47MzmMp-ytN0PC94_7Cfv17ev18qpY_bj8vrxYFa5qVaaqcFFVCAYBHJQtonS-KxuryqZTICqsvXLW19BZqGtlrala70DaxpfKlifsfO9Lc_yeMWU99snhMJgJw5y0qECAgroCQj--QG_DHCeabkdR74b-nCixpxz9Q4ro9TrS--JWC9C7LPU-S01F77LUG9J8eHSe7Yjds-IpPALkHkh0Nd1g_Kv1f13_ABkmriI</recordid><startdate>20130701</startdate><enddate>20130701</enddate><creator>Ahn, Sang-Hoon</creator><creator>Lee, Ju Hee</creator><creator>Park, Do Joong</creator><creator>Kim, Hyung-Ho</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20130701</creationdate><title>Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer</title><author>Ahn, Sang-Hoon ; Lee, Ju Hee ; Park, Do Joong ; Kim, Hyung-Ho</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c489t-c49e544e0ae00c038ee2cfd37b937d9014e6f9cbf60db0669bba48fc02b7f39b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Abdominal Surgery</topic><topic>Aged</topic><topic>Blood Loss, Surgical</topic><topic>Cancer Research</topic><topic>Clinical outcomes</topic><topic>Databases, Factual</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastrectomy - methods</topic><topic>Gastric cancer</topic><topic>Gastroenterology</topic><topic>Gastroesophageal Reflux - epidemiology</topic><topic>Gastroesophageal Reflux - etiology</topic><topic>Gastroesophageal Reflux - prevention & control</topic><topic>Humans</topic><topic>Laparoscopy - methods</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Oncology</topic><topic>Operative Time</topic><topic>Original Article</topic><topic>Republic of Korea</topic><topic>Retrospective Studies</topic><topic>Stomach Neoplasms - pathology</topic><topic>Stomach Neoplasms - surgery</topic><topic>Surgical Oncology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ahn, Sang-Hoon</creatorcontrib><creatorcontrib>Lee, Ju Hee</creatorcontrib><creatorcontrib>Park, Do Joong</creatorcontrib><creatorcontrib>Kim, Hyung-Ho</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ahn, Sang-Hoon</au><au>Lee, Ju Hee</au><au>Park, Do Joong</au><au>Kim, Hyung-Ho</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer</atitle><jtitle>Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</jtitle><stitle>Gastric Cancer</stitle><addtitle>Gastric Cancer</addtitle><date>2013-07-01</date><risdate>2013</risdate><volume>16</volume><issue>3</issue><spage>282</spage><epage>289</epage><pages>282-289</pages><issn>1436-3291</issn><eissn>1436-3305</eissn><abstract>Background
The choice of surgical strategy for patients with proximal gastric cancer is controversial. The purpose of this study was to assess the feasibility, safety, and surgical and functional outcomes of laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG).
Methods
Between June 2003 and December 2009, 131 patients with proximal gastric cancer underwent LAPG (
n
= 50) or LATG (
n
= 81) at Seoul National University Bundang Hospital. We reviewed their medical and surgical records from our prospectively collected gastric cancer database. The clinicopathologic characteristics and short-term, long-term, and functional outcomes were compared between the 2 groups.
Results
There were no significant differences in demographics, T-stage, N-stage, or survival between the 2 groups. The LAPG group had a shorter operative time and lower estimated blood loss than the LATG group. The early complication rates after the LAPG and LATG procedures were 24.0 and 17.3 %, respectively (
p
= 0.349). The incidence of reflux symptoms was significantly higher in the LAPG group (32.0 vs. 3.7 %,
p
< 0.001). The parameters that reflected nutritional status were similar in the 2 groups.
Conclusion
LAPG is a feasible and acceptable method for treating proximal early gastric cancer in terms of surgical and oncologic safety. However, esophagogastrostomy after LAPG was associated with an increased risk of reflux symptoms. Antireflux procedures should be considered to prevent reflux symptoms after LAPG.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>22821182</pmid><doi>10.1007/s10120-012-0178-x</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 1436-3291 |
| ispartof | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2013-07, Vol.16 (3), p.282-289 |
| issn | 1436-3291 1436-3305 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals; EZB Electronic Journals Library |
| subjects | Abdominal Surgery Aged Blood Loss, Surgical Cancer Research Clinical outcomes Databases, Factual Feasibility Studies Female Follow-Up Studies Gastrectomy - methods Gastric cancer Gastroenterology Gastroesophageal Reflux - epidemiology Gastroesophageal Reflux - etiology Gastroesophageal Reflux - prevention & control Humans Laparoscopy - methods Male Medicine Medicine & Public Health Middle Aged Oncology Operative Time Original Article Republic of Korea Retrospective Studies Stomach Neoplasms - pathology Stomach Neoplasms - surgery Surgical Oncology Time Factors |
| title | Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer |
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