Unruptured intracranial aneurysms: Comparison of perioperative complications, discharge disposition, outcome, and effect of calcification, between clipping and coiling: A single institution experience
Objective: The aim of the study was to compare the perioperative complications, obliteration rates, discharge dispositions, clinic-radiological outcomes, and the role of calcification between the microsurgical and endovascular treatment of unruptured intracranial aneurysms. Materials and Methods: Re...
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Veröffentlicht in: | Neurology India 2013-05, Vol.61 (3), p.270-276 |
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description | Objective: The aim of the study was to compare the perioperative complications, obliteration rates, discharge dispositions, clinic-radiological outcomes, and the role of calcification between the microsurgical and endovascular treatment of unruptured intracranial aneurysms. Materials and Methods: Retrospective data of the patients treated with microsurgical clipping and those treated by endovascular coiling from January 2007 to August 2012 was collected from the database. Results: Intraoperative rupture was not different in both the treatment groups (4.05% vs. 1.5% clip vs. coil). A total of 9.4% of the patients in the clipping group and 4.5% of the patients in the coiling group suffered postoperative stroke. At last follow up, 89% of the patients in the clipping group and 93% of the patients in the coiling group had favorable outcomes. The mean length of stay was more in clipping group (6.1 vs. 2.7, clip vs. coil, P < 0.05). Patients discharged to home without assistance/rehabilitation services were more in coiling ( P = 0.001). A total of 28.4% (23/81) of the coiled aneurysms were found to have residue neck on postoperative angiograms as compared with 12.6% (10/79) of the clipped aneurysms ( P = 0.01). Calcification within the aneurysm was strongly correlated to the size, perioperative complications, and the outcome ( P < 0.05). However, on excluding the calcified cases the size and outcome do not show a significant correlation. Conclusion: With appropriate patient selection, the majority of the UIAs can be managed by either of the treatment modalities with very low mortality and morbidity. Both the treatment modalities should be employed synergistically. |
doi_str_mv | 10.4103/0028-3886.115067 |
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Materials and Methods: Retrospective data of the patients treated with microsurgical clipping and those treated by endovascular coiling from January 2007 to August 2012 was collected from the database. Results: Intraoperative rupture was not different in both the treatment groups (4.05% vs. 1.5% clip vs. coil). A total of 9.4% of the patients in the clipping group and 4.5% of the patients in the coiling group suffered postoperative stroke. At last follow up, 89% of the patients in the clipping group and 93% of the patients in the coiling group had favorable outcomes. The mean length of stay was more in clipping group (6.1 vs. 2.7, clip vs. coil, P < 0.05). Patients discharged to home without assistance/rehabilitation services were more in coiling ( P = 0.001). A total of 28.4% (23/81) of the coiled aneurysms were found to have residue neck on postoperative angiograms as compared with 12.6% (10/79) of the clipped aneurysms ( P = 0.01). Calcification within the aneurysm was strongly correlated to the size, perioperative complications, and the outcome ( P < 0.05). However, on excluding the calcified cases the size and outcome do not show a significant correlation. Conclusion: With appropriate patient selection, the majority of the UIAs can be managed by either of the treatment modalities with very low mortality and morbidity. Both the treatment modalities should be employed synergistically.</description><identifier>ISSN: 0028-3886</identifier><identifier>EISSN: 1998-4022</identifier><identifier>DOI: 10.4103/0028-3886.115067</identifier><identifier>PMID: 23860147</identifier><language>eng</language><publisher>India: Medknow Publications</publisher><subject>Adult ; Aged ; Calcification ; Care and treatment ; Complications ; Complications and side effects ; Embolization, Therapeutic - adverse effects ; Embolization, Therapeutic - statistics & numerical data ; Female ; Humans ; Intracranial Aneurysm - complications ; Intracranial Aneurysm - surgery ; Intracranial Aneurysm - therapy ; Intracranial aneurysms ; Intraoperative Complications - epidemiology ; Male ; Microsurgery - adverse effects ; Microsurgery - statistics & numerical data ; Middle Aged ; Patient Discharge - statistics & numerical data ; Retrospective Studies ; Surgery ; Treatment Outcome</subject><ispartof>Neurology India, 2013-05, Vol.61 (3), p.270-276</ispartof><rights>COPYRIGHT 2013 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt Ltd May-Jun 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491r-d6a66f949f5b3dfff768f664c56595de48c2404685c47155d6176aaad1caecd03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23860147$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sharma, Mayur</creatorcontrib><creatorcontrib>Brown, Benjamin</creatorcontrib><creatorcontrib>Madhugiri, Venkatesh</creatorcontrib><creatorcontrib>Cuellar-Saenz, Hugo</creatorcontrib><creatorcontrib>Sonig, Ashish</creatorcontrib><creatorcontrib>Ambekar, Sudheer</creatorcontrib><creatorcontrib>Nanda, Anil</creatorcontrib><title>Unruptured intracranial aneurysms: Comparison of perioperative complications, discharge disposition, outcome, and effect of calcification, between clipping and coiling: A single institution experience</title><title>Neurology India</title><addtitle>Neurol India</addtitle><description>Objective: The aim of the study was to compare the perioperative complications, obliteration rates, discharge dispositions, clinic-radiological outcomes, and the role of calcification between the microsurgical and endovascular treatment of unruptured intracranial aneurysms. Materials and Methods: Retrospective data of the patients treated with microsurgical clipping and those treated by endovascular coiling from January 2007 to August 2012 was collected from the database. Results: Intraoperative rupture was not different in both the treatment groups (4.05% vs. 1.5% clip vs. coil). A total of 9.4% of the patients in the clipping group and 4.5% of the patients in the coiling group suffered postoperative stroke. At last follow up, 89% of the patients in the clipping group and 93% of the patients in the coiling group had favorable outcomes. The mean length of stay was more in clipping group (6.1 vs. 2.7, clip vs. coil, P < 0.05). Patients discharged to home without assistance/rehabilitation services were more in coiling ( P = 0.001). A total of 28.4% (23/81) of the coiled aneurysms were found to have residue neck on postoperative angiograms as compared with 12.6% (10/79) of the clipped aneurysms ( P = 0.01). Calcification within the aneurysm was strongly correlated to the size, perioperative complications, and the outcome ( P < 0.05). However, on excluding the calcified cases the size and outcome do not show a significant correlation. Conclusion: With appropriate patient selection, the majority of the UIAs can be managed by either of the treatment modalities with very low mortality and morbidity. Both the treatment modalities should be employed synergistically.</description><subject>Adult</subject><subject>Aged</subject><subject>Calcification</subject><subject>Care and treatment</subject><subject>Complications</subject><subject>Complications and side effects</subject><subject>Embolization, Therapeutic - adverse effects</subject><subject>Embolization, Therapeutic - statistics & numerical data</subject><subject>Female</subject><subject>Humans</subject><subject>Intracranial Aneurysm - complications</subject><subject>Intracranial Aneurysm - surgery</subject><subject>Intracranial Aneurysm - therapy</subject><subject>Intracranial aneurysms</subject><subject>Intraoperative Complications - epidemiology</subject><subject>Male</subject><subject>Microsurgery - adverse effects</subject><subject>Microsurgery - statistics & numerical data</subject><subject>Middle Aged</subject><subject>Patient Discharge - statistics & numerical data</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><issn>0028-3886</issn><issn>1998-4022</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkktv1DAUhSMEokNhzwpZYsNiMtiJ4yTdDSNeUiU2dG15nOvBrWMHO2HoP-RnccNMC0WjSH5-5-g692TZS0ZXnNHyLaVFk5dNI1aMVVTUj7IFa9sm57QoHmeL--uz7FlK17gtS1Y8zc6KshGU8XqR_brycRrGKUJHrB-j0lF5qxxRHqZ4m_p0QTahH1S0KXgSDBkg2oCDGu0PIBrvnNW4CT4tSWeT_qbiDubVEJKdz5ckTCOCsETXjoAxoMfZSiunrTmql2QL4x7AE-3sMFi_-0PrYB2uL8iaJJwdYJlptOM0awj8nMsBr-F59sQol-DFcT7Prj68_7r5lF9--fh5s77MNW9ZzDuhhDAtb021LTtjTC0aIwTXlajaqgPe6IJTLppK85pVVSdYLZRSHdMKdEfL8-zNwXeI4fsEaZQ9vhmcwx8WpiQZp4y2FO0Qff0feh2m6LE6pApRN0XFy7_UTjmQ1pswd2E2leuS07LC1gqk8hPUDjw2wgUPxuLxA351gsevg97qkwJ6EOgYUopg5BBtr-KtZFTOYZNzmuScJnkIG0peHd83bXvo7gV36ULg3QHYBzdCTDdu2kOUyN74sH9gnP9jLIuayrtclr8BoXPntQ</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>Sharma, Mayur</creator><creator>Brown, Benjamin</creator><creator>Madhugiri, Venkatesh</creator><creator>Cuellar-Saenz, Hugo</creator><creator>Sonig, Ashish</creator><creator>Ambekar, Sudheer</creator><creator>Nanda, Anil</creator><general>Medknow Publications</general><general>Medknow Publications and Media Pvt. 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Materials and Methods: Retrospective data of the patients treated with microsurgical clipping and those treated by endovascular coiling from January 2007 to August 2012 was collected from the database. Results: Intraoperative rupture was not different in both the treatment groups (4.05% vs. 1.5% clip vs. coil). A total of 9.4% of the patients in the clipping group and 4.5% of the patients in the coiling group suffered postoperative stroke. At last follow up, 89% of the patients in the clipping group and 93% of the patients in the coiling group had favorable outcomes. The mean length of stay was more in clipping group (6.1 vs. 2.7, clip vs. coil, P < 0.05). Patients discharged to home without assistance/rehabilitation services were more in coiling ( P = 0.001). A total of 28.4% (23/81) of the coiled aneurysms were found to have residue neck on postoperative angiograms as compared with 12.6% (10/79) of the clipped aneurysms ( P = 0.01). Calcification within the aneurysm was strongly correlated to the size, perioperative complications, and the outcome ( P < 0.05). However, on excluding the calcified cases the size and outcome do not show a significant correlation. Conclusion: With appropriate patient selection, the majority of the UIAs can be managed by either of the treatment modalities with very low mortality and morbidity. Both the treatment modalities should be employed synergistically.</abstract><cop>India</cop><pub>Medknow Publications</pub><pmid>23860147</pmid><doi>10.4103/0028-3886.115067</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Calcification Care and treatment Complications Complications and side effects Embolization, Therapeutic - adverse effects Embolization, Therapeutic - statistics & numerical data Female Humans Intracranial Aneurysm - complications Intracranial Aneurysm - surgery Intracranial Aneurysm - therapy Intracranial aneurysms Intraoperative Complications - epidemiology Male Microsurgery - adverse effects Microsurgery - statistics & numerical data Middle Aged Patient Discharge - statistics & numerical data Retrospective Studies Surgery Treatment Outcome |
title | Unruptured intracranial aneurysms: Comparison of perioperative complications, discharge disposition, outcome, and effect of calcification, between clipping and coiling: A single institution experience |
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