Uridine Diphosphate Glucuronosyltransferase 2B7 Variant p.His268Tyr as a Predictor of Kidney Allograft Early Acute Rejection

Abstract Background Uridine diphosphate glucuronosyltransferase ( UGT2B7 ) is responsible for conversion of mycophenolic acid to mycophenolic acyl-glucuronide (acylMPAG). Conflicting data exist regarding the role of UGT2B7 p.His268Tyr (802C>T, rs7439366) variant in the clinical course following o...

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Veröffentlicht in:	Transplantation proceedings 2013-05, Vol.45 (4), p.1516-1519
Hauptverfasser:	Pazik, J, Ołdak, M, Lewandowski, Z, Podgórska, M, Sitarek, E, Płoski, R, Gała̧zka, Z, Kwiatkowski, A, Malejczyk, J, Durlik, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers - metabolism Female Glucuronosyltransferase - chemistry Glucuronosyltransferase - metabolism Graft Rejection - diagnosis Histidine - chemistry Humans Isoenzymes - chemistry Isoenzymes - metabolism Kidney Transplantation Male Middle Aged Polymorphism, Single Nucleotide Surgery Treatment Outcome Tyrosine - chemistry
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