Polymer-free and polyvinylpirrolidone-based electrospun solid dosage forms for drug dissolution enhancement

[Display omitted] Fast-release nano- and microfibres of lipophilic spironolactone were prepared in a continuous manner by electrostatic spinning, in which the application of polyvinylpyrrolidone K90 as matrix polymer enabled formation of solid solutions. However, instead of the anticipated immediate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmaceutical sciences 2013-07, Vol.49 (4), p.595-602
Hauptverfasser:	Vigh, Tamás, Horváthová, Tímea, Balogh, Attila, Sóti, Péter Lajos, Drávavölgyi, Gábor, Nagy, Zsombor Kristóf, Marosi, György
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Hydroxypropyl-beta-cyclodextrin beta-Cyclodextrins - chemistry Calorimetry, Differential Scanning Crystallization Cyclodextrins Dosage Forms Drug Compounding - methods Electrospinning Immediate release Mineralocorticoid Receptor Antagonists - chemistry Nanofibers Orally dissolving web Povidone - chemistry Powder Diffraction Solubility Spectrum Analysis, Raman Spironolactone - chemistry Transmission Raman spectroscopy X-Ray Diffraction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!