Vesicle formation as a result of interaction between polymorphonuclear neutrophils and Staphylococcus aureus biofilm

Staphylococcus aureus, a major opportunistic pathogen, is a leading cause of biofilm-related infections in clinical practice. Staphylococcal biofilms are highly resistant to antibacterial medicines and immune effector cells. The main result of our work is the discovery of nano-vesicles in the supern...

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Veröffentlicht in:	Journal of medical microbiology 2013-08, Vol.62 (8), p.1153-1159
Hauptverfasser:	CHEBOTAR, Igor' V, KONCHAKOVA, Evgenia D, MAIANSKII, Andrey N
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacterial Proteins - metabolism Biofilms - drug effects Biofilms - growth & development Cell Survival Endopeptidase K - metabolism Extracellular Matrix Host-Pathogen Interactions Humans Microscopy, Confocal Microscopy, Electron, Transmission Neutrophils - immunology Neutrophils - microbiology Neutrophils - ultrastructure Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Staphylococcal Infections - microbiology Staphylococcus aureus - drug effects Staphylococcus aureus - growth & development Staphylococcus aureus - physiology Staphylococcus epidermidis - drug effects Staphylococcus epidermidis - growth & development Type C Phospholipases - metabolism
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