THE PROTECTIVE ROLE OF MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS IN YOUNG INFANTS
In 20 infants with polymerase chain reaction-confirmed pertussis
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Veröffentlicht in: | The Pediatric infectious disease journal 2013-06, Vol.32 (6), p.695-698 |
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container_title | The Pediatric infectious disease journal |
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creator | HEININGER, Ulrich RIFFELMANN, Marion BÄR, Gurli RUDIN, Christoph WIRSING VON KÖNIG, Carl-Heinz |
description | In 20 infants with polymerase chain reaction-confirmed pertussis |
doi_str_mv | 10.1097/INF.0b013e318288b610 |
format | Article |
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Although differences of median (and mean) antibody values between groups were not significant, they are in line with the concept of infant protection by maternal antibodies and thus support the strategy of pertussis booster immunization in pregnant women.</description><subject>Antibodies, Bacterial - blood</subject><subject>Antitoxins - blood</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Bordetella pertussis - immunology</subject><subject>Ent and stomatologic bacterial diseases</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Immunity, Maternally-Acquired</subject><subject>Immunoglobulin G - blood</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Whooping Cough - immunology</subject><subject>Whooping Cough - prevention & control</subject><issn>0891-3668</issn><issn>1532-0987</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE9r20AQxZfS0rhuv0EIeyn0onRm_2n3qNhrR6BKQVoXchLSeg0Odpxo40O_fRXspNDTDMzvvXk8Qi4RrhFM-jMvF9fQA_LAUTOte4XwgUxQcpaA0elHMgFtMOFK6QvyJcYHAOAC4TO5YFwwI6WZkN7dWnpXV87OXP7b0roqLK0W9FfmbF1mRXFP57YeL3OalS6_qea5bWi2zPKycfSmqufW2aLI6J2t3app8obmJb2vVuVyXBajpvlKPm26XQzfznNKVgvrZrdJUS3zWVYknmv-kqDnPeo1GlDSg5CpMcBYn3oley2kNxgYAq43XAsITHZegBKo1qliQXc9n5IfJ9-n4fB8DPGl3W-jD7td9xgOx9giN8YwZTgbUXFC_XCIcQib9mnY7rvhT4vQvrbbjtnb_9sdZVfnD8d-H9bvorc6R-D7Geii73aboXv02_iPS8XoKBX_C3WveQQ</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>HEININGER, Ulrich</creator><creator>RIFFELMANN, Marion</creator><creator>BÄR, Gurli</creator><creator>RUDIN, Christoph</creator><creator>WIRSING VON KÖNIG, Carl-Heinz</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130601</creationdate><title>THE PROTECTIVE ROLE OF MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS IN YOUNG INFANTS</title><author>HEININGER, Ulrich ; RIFFELMANN, Marion ; BÄR, Gurli ; RUDIN, Christoph ; WIRSING VON KÖNIG, Carl-Heinz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c383t-1c3b18d19065c045799022b7c65b845c91e2101df3840e25ac406416d762e8ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Antibodies, Bacterial - blood</topic><topic>Antitoxins - blood</topic><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Bordetella pertussis - immunology</topic><topic>Ent and stomatologic bacterial diseases</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Female</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Immunity, Maternally-Acquired</topic><topic>Immunoglobulin G - blood</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Whooping Cough - immunology</topic><topic>Whooping Cough - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HEININGER, Ulrich</creatorcontrib><creatorcontrib>RIFFELMANN, Marion</creatorcontrib><creatorcontrib>BÄR, Gurli</creatorcontrib><creatorcontrib>RUDIN, Christoph</creatorcontrib><creatorcontrib>WIRSING VON KÖNIG, Carl-Heinz</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Pediatric infectious disease journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HEININGER, Ulrich</au><au>RIFFELMANN, Marion</au><au>BÄR, Gurli</au><au>RUDIN, Christoph</au><au>WIRSING VON KÖNIG, Carl-Heinz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THE PROTECTIVE ROLE OF MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS IN YOUNG INFANTS</atitle><jtitle>The Pediatric infectious disease journal</jtitle><addtitle>Pediatr Infect Dis J</addtitle><date>2013-06-01</date><risdate>2013</risdate><volume>32</volume><issue>6</issue><spage>695</spage><epage>698</epage><pages>695-698</pages><issn>0891-3668</issn><eissn>1532-0987</eissn><coden>PIDJEV</coden><abstract>In 20 infants with polymerase chain reaction-confirmed pertussis <6 months of age, median cord blood anti-pertussis toxin, anti-filamentous hemagglutinin and anti-pertactin IgG antibody values were lower than in 80 matched controls: 10.5 versus 13.5 anti-pertussis toxin IU/mL, 14.5/18.0 (anti-filamentous hemagglutinin) and 6.0/9.0 (anti-pertactin), respectively. Although differences of median (and mean) antibody values between groups were not significant, they are in line with the concept of infant protection by maternal antibodies and thus support the strategy of pertussis booster immunization in pregnant women.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>23429559</pmid><doi>10.1097/INF.0b013e318288b610</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Antibodies, Bacterial - blood Antitoxins - blood Bacterial diseases Biological and medical sciences Bordetella pertussis - immunology Ent and stomatologic bacterial diseases Enzyme-Linked Immunosorbent Assay Female Human bacterial diseases Humans Immunity, Maternally-Acquired Immunoglobulin G - blood Infant Infant, Newborn Infectious diseases Male Medical sciences Pregnancy Whooping Cough - immunology Whooping Cough - prevention & control |
title | THE PROTECTIVE ROLE OF MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS IN YOUNG INFANTS |
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