Development of Bacteriostatic DNA Aptamers for Salmonella

Salmonella is one of the most dangerous and common food-borne pathogens. The overuse of antibiotics for disease prevention has led to the development of multidrug resistant Salmonella. Now, more than ever, there is a need for new antimicrobial drugs to combat these resistant bacteria. Aptamers have...

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Veröffentlicht in:	Journal of medicinal chemistry 2013-02, Vol.56 (4), p.1564-1572
Hauptverfasser:	Kolovskaya, Olga S, Savitskaya, Anna G, Zamay, Tatiana N, Reshetneva, Irina T, Zamay, Galina S, Erkaev, Evgeny N, Wang, Xiaoyan, Wehbe, Mohamed, Salmina, Alla B, Perianova, Olga V, Zubkova, Olga A, Spivak, Ekaterina A, Mezko, Vasily S, Glazyrin, Yury E, Titova, Nadezhda M, Berezovski, Maxim V, Zamay, Anna S
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Aptamers, Nucleotide - chemical synthesis Aptamers, Nucleotide - chemistry Aptamers, Nucleotide - pharmacology Base Sequence Drug Resistance, Multiple, Bacterial Molecular Sequence Data Salmonella enteritidis - drug effects Salmonella typhimurium - drug effects SELEX Aptamer Technique Structure-Activity Relationship
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