Development and evaluation of endurance test system for ventricular assist devices
We developed a novel endurance test system that can arbitrarily set various circulatory conditions and has durability and stability for long-term continuous evaluation of ventricular assist devices (VADs), and we evaluated its fundamental performance and prolonged durability and stability. The circu...
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| Veröffentlicht in: | Journal of artificial organs 2013-06, Vol.16 (2), p.138-148 |
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| container_title | Journal of artificial organs |
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| creator | Sumikura, Hirohito Homma, Akihiko Ohnuma, Kentaro Taenaka, Yoshiyuki Takewa, Yoshiaki Mukaibayashi, Hiroshi Katano, Kazuo Tatsumi, Eisuke |
| description | We developed a novel endurance test system that can arbitrarily set various circulatory conditions and has durability and stability for long-term continuous evaluation of ventricular assist devices (VADs), and we evaluated its fundamental performance and prolonged durability and stability. The circulation circuit of the present endurance test system consisted of a pulsatile pump with a small closed chamber (SCC), a closed chamber, a reservoir and an electromagnetic proportional valve. Two duckbill valves were mounted in the inlet and outlet of the pulsatile pump. The features of the circulation circuit are as follows: (1) the components of the circulation circuit consist of optimized industrial devices, giving durability; (2) the pulsatile pump can change the heart rate and stroke length (SL), as well as its compliance using the SCC. Therefore, the endurance test system can quantitatively reproduce various circulatory conditions. The range of reproducible circulatory conditions in the endurance test circuit was examined in terms of fundamental performance. Additionally, continuous operation for 6 months was performed in order to evaluate the durability and stability. The circulation circuit was able to set up a wide range of pressure and total flow conditions using the SCC and adjusting the pulsatile pump SL. The long-term continuous operation test demonstrated that stable, continuous operation for 6 months was possible without leakage or industrial device failure. The newly developed endurance test system demonstrated a wide range of reproducible circulatory conditions, durability and stability, and is a promising approach for evaluating the basic characteristics of VADs. |
| doi_str_mv | 10.1007/s10047-013-0687-3 |
| format | Article |
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The circulation circuit of the present endurance test system consisted of a pulsatile pump with a small closed chamber (SCC), a closed chamber, a reservoir and an electromagnetic proportional valve. Two duckbill valves were mounted in the inlet and outlet of the pulsatile pump. The features of the circulation circuit are as follows: (1) the components of the circulation circuit consist of optimized industrial devices, giving durability; (2) the pulsatile pump can change the heart rate and stroke length (SL), as well as its compliance using the SCC. Therefore, the endurance test system can quantitatively reproduce various circulatory conditions. The range of reproducible circulatory conditions in the endurance test circuit was examined in terms of fundamental performance. Additionally, continuous operation for 6 months was performed in order to evaluate the durability and stability. The circulation circuit was able to set up a wide range of pressure and total flow conditions using the SCC and adjusting the pulsatile pump SL. The long-term continuous operation test demonstrated that stable, continuous operation for 6 months was possible without leakage or industrial device failure. The newly developed endurance test system demonstrated a wide range of reproducible circulatory conditions, durability and stability, and is a promising approach for evaluating the basic characteristics of VADs.</description><identifier>ISSN: 1434-7229</identifier><identifier>EISSN: 1619-0904</identifier><identifier>DOI: 10.1007/s10047-013-0687-3</identifier><identifier>PMID: 23400569</identifier><language>eng</language><publisher>Japan: Springer Japan</publisher><subject>Biomedical Engineering and Bioengineering ; Cardiac Surgery ; Equipment Failure Analysis ; Heart-Assist Devices ; Humans ; Medicine ; Medicine & Public Health ; Nephrology ; Original Article ; Prosthesis Design ; Prosthesis Failure ; Pulsatile Flow ; Reproducibility of Results</subject><ispartof>Journal of artificial organs, 2013-06, Vol.16 (2), p.138-148</ispartof><rights>The Japanese Society for Artificial Organs 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c429t-391e8bc3043093fc41c9f1888b52fbc0887b9f733d7b3d12ed647bc7a5886bdb3</citedby><cites>FETCH-LOGICAL-c429t-391e8bc3043093fc41c9f1888b52fbc0887b9f733d7b3d12ed647bc7a5886bdb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10047-013-0687-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10047-013-0687-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23400569$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sumikura, Hirohito</creatorcontrib><creatorcontrib>Homma, Akihiko</creatorcontrib><creatorcontrib>Ohnuma, Kentaro</creatorcontrib><creatorcontrib>Taenaka, Yoshiyuki</creatorcontrib><creatorcontrib>Takewa, Yoshiaki</creatorcontrib><creatorcontrib>Mukaibayashi, Hiroshi</creatorcontrib><creatorcontrib>Katano, Kazuo</creatorcontrib><creatorcontrib>Tatsumi, Eisuke</creatorcontrib><title>Development and evaluation of endurance test system for ventricular assist devices</title><title>Journal of artificial organs</title><addtitle>J Artif Organs</addtitle><addtitle>J Artif Organs</addtitle><description>We developed a novel endurance test system that can arbitrarily set various circulatory conditions and has durability and stability for long-term continuous evaluation of ventricular assist devices (VADs), and we evaluated its fundamental performance and prolonged durability and stability. The circulation circuit of the present endurance test system consisted of a pulsatile pump with a small closed chamber (SCC), a closed chamber, a reservoir and an electromagnetic proportional valve. Two duckbill valves were mounted in the inlet and outlet of the pulsatile pump. The features of the circulation circuit are as follows: (1) the components of the circulation circuit consist of optimized industrial devices, giving durability; (2) the pulsatile pump can change the heart rate and stroke length (SL), as well as its compliance using the SCC. Therefore, the endurance test system can quantitatively reproduce various circulatory conditions. The range of reproducible circulatory conditions in the endurance test circuit was examined in terms of fundamental performance. Additionally, continuous operation for 6 months was performed in order to evaluate the durability and stability. The circulation circuit was able to set up a wide range of pressure and total flow conditions using the SCC and adjusting the pulsatile pump SL. The long-term continuous operation test demonstrated that stable, continuous operation for 6 months was possible without leakage or industrial device failure. The newly developed endurance test system demonstrated a wide range of reproducible circulatory conditions, durability and stability, and is a promising approach for evaluating the basic characteristics of VADs.</description><subject>Biomedical Engineering and Bioengineering</subject><subject>Cardiac Surgery</subject><subject>Equipment Failure Analysis</subject><subject>Heart-Assist Devices</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Nephrology</subject><subject>Original Article</subject><subject>Prosthesis Design</subject><subject>Prosthesis Failure</subject><subject>Pulsatile Flow</subject><subject>Reproducibility of 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and evaluation of endurance test system for ventricular assist devices</title><author>Sumikura, Hirohito ; Homma, Akihiko ; Ohnuma, Kentaro ; Taenaka, Yoshiyuki ; Takewa, Yoshiaki ; Mukaibayashi, Hiroshi ; Katano, Kazuo ; Tatsumi, Eisuke</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c429t-391e8bc3043093fc41c9f1888b52fbc0887b9f733d7b3d12ed647bc7a5886bdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Biomedical Engineering and Bioengineering</topic><topic>Cardiac Surgery</topic><topic>Equipment Failure Analysis</topic><topic>Heart-Assist Devices</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Nephrology</topic><topic>Original Article</topic><topic>Prosthesis Design</topic><topic>Prosthesis Failure</topic><topic>Pulsatile Flow</topic><topic>Reproducibility of Results</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sumikura, Hirohito</creatorcontrib><creatorcontrib>Homma, Akihiko</creatorcontrib><creatorcontrib>Ohnuma, Kentaro</creatorcontrib><creatorcontrib>Taenaka, Yoshiyuki</creatorcontrib><creatorcontrib>Takewa, Yoshiaki</creatorcontrib><creatorcontrib>Mukaibayashi, Hiroshi</creatorcontrib><creatorcontrib>Katano, Kazuo</creatorcontrib><creatorcontrib>Tatsumi, Eisuke</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 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The circulation circuit of the present endurance test system consisted of a pulsatile pump with a small closed chamber (SCC), a closed chamber, a reservoir and an electromagnetic proportional valve. Two duckbill valves were mounted in the inlet and outlet of the pulsatile pump. The features of the circulation circuit are as follows: (1) the components of the circulation circuit consist of optimized industrial devices, giving durability; (2) the pulsatile pump can change the heart rate and stroke length (SL), as well as its compliance using the SCC. Therefore, the endurance test system can quantitatively reproduce various circulatory conditions. The range of reproducible circulatory conditions in the endurance test circuit was examined in terms of fundamental performance. Additionally, continuous operation for 6 months was performed in order to evaluate the durability and stability. The circulation circuit was able to set up a wide range of pressure and total flow conditions using the SCC and adjusting the pulsatile pump SL. The long-term continuous operation test demonstrated that stable, continuous operation for 6 months was possible without leakage or industrial device failure. The newly developed endurance test system demonstrated a wide range of reproducible circulatory conditions, durability and stability, and is a promising approach for evaluating the basic characteristics of VADs.</abstract><cop>Japan</cop><pub>Springer Japan</pub><pmid>23400569</pmid><doi>10.1007/s10047-013-0687-3</doi><tpages>11</tpages></addata></record> |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Biomedical Engineering and Bioengineering Cardiac Surgery Equipment Failure Analysis Heart-Assist Devices Humans Medicine Medicine & Public Health Nephrology Original Article Prosthesis Design Prosthesis Failure Pulsatile Flow Reproducibility of Results |
| title | Development and evaluation of endurance test system for ventricular assist devices |
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