HOMECAT: consensus homologs mapping for interspecific knowledge transfer and functional genomic data integration
Comparative studies are encouraged by the fast increase of data availability from the latest high-throughput techniques, in particular from functional genomic studies. Yet, the size of datasets, the challenge of complete orthologs findings and not last, the variety of identification formats, make in...
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| Veröffentlicht in: | Bioinformatics 2013-06, Vol.29 (12), p.1574-1576 |
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| container_title | Bioinformatics |
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| creator | Zorzan, Simone Lorenzetto, Erika Ettorre, Michele Pontelli, Valeria Laudanna, Carlo Buffelli, Mario |
| description | Comparative studies are encouraged by the fast increase of data availability from the latest high-throughput techniques, in particular from functional genomic studies. Yet, the size of datasets, the challenge of complete orthologs findings and not last, the variety of identification formats, make information integration challenging. With HOMECAT, we aim to facilitate cross-species relationship identification and data mapping, by combining orthology predictions from several publicly available sources, a convenient interface for high-throughput data download and automatic identifier conversion into a Cytoscape plug-in, that provides both an integration with a large set of bioinformatics tools, as well as a user-friendly interface.
HOMECAT and the Supplementary Materials are freely available at http://www.cbmc.it/homecat/. |
| doi_str_mv | 10.1093/bioinformatics/btt189 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1367-4803 |
| ispartof | Bioinformatics, 2013-06, Vol.29 (12), p.1574-1576 |
| issn | 1367-4803 1367-4811 1460-2059 |
| language | eng |
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| source | MEDLINE; Access via Oxford University Press (Open Access Collection); EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Animals Genomics - methods Mice Oligonucleotide Array Sequence Analysis Rats Software Systems Integration |
| title | HOMECAT: consensus homologs mapping for interspecific knowledge transfer and functional genomic data integration |
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