PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)

PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)

About 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. Ten constituents from 10 peaks were identified. Terpinyl acetate (5...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of pharmaceutical sciences and research 2013-02, Vol.4 (2), p.819-819
Hauptverfasser: Helen, P A Mary, Aswathy, M R, Rathi, K G Deepthi R Mol, Joseph, J Jaison, Sree, S Jaya
Format: Artikel
Sprache:eng
Schlagworte:
Mangifera indica
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 819
container_issue 2
container_start_page 819
container_title International journal of pharmaceutical sciences and research
container_volume 4
creator Helen, P A Mary
Aswathy, M R
Rathi, K G Deepthi R Mol
Joseph, J Jaison
Sree, S Jaya
description About 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. Ten constituents from 10 peaks were identified. Terpinyl acetate (5.80%) and phytol isomer (5.12%) are as the major constituents and the minor constituents like oxirane (3.57%), sabinene (3.24%), beta-pinen (3.34%), beta-myrcene (3.23%) , cymene (3.68%), alpha-limonene (2.82%), eucalyptol (1,8-cineo (4.71%), 1,3-benzodioxole, 5-(2-, (3.68%) were identified. The antimicrobial activity of different extract was tested against human and plant pathogenic bacteria. Hexane-ethyl acetate extract showed significant role on inhibiting almost all tested pathogenic organisms. Using histochemical reagents such as Phloroglucinol-HCl, Dragendorffreagent was used for the localization of lignin and alkaloids respectively. Mangifera indica showed 100% larvicide activity. The addition of various concentrations of hexane-ethyl acetate extract of Mangifera indica on the L929 cell lines showed cytotoxic activity.
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_1399912830</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1399912830</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_13999128303</originalsourceid><addsrcrecordid>eNqVS80KgkAYXIIgKd9hj3UI1KXS48e25qKuoV-Sp5CwKCyrzfdvg16ggWF-mBkQywlWi7nvMW9EbK2vjsHSc12fWeS8jSrMeCRSySGhoCCpClkYszZEUyoucgocZSmxollIEwEhFXvMTfnNKaiNDEUOVKq1OdBpnCHiLs4UpLSEXMYwm5DhqW51Y_90TKahQB7NH6_u2Tf6fbhd9LFp2_redL0-uCwIAtfzmcP-mH4A2FBBIw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1399912830</pqid></control><display><type>article</type><title>PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)</title><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Helen, P A Mary ; Aswathy, M R ; Rathi, K G Deepthi R Mol ; Joseph, J Jaison ; Sree, S Jaya</creator><creatorcontrib>Helen, P A Mary ; Aswathy, M R ; Rathi, K G Deepthi R Mol ; Joseph, J Jaison ; Sree, S Jaya</creatorcontrib><description>About 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. Ten constituents from 10 peaks were identified. Terpinyl acetate (5.80%) and phytol isomer (5.12%) are as the major constituents and the minor constituents like oxirane (3.57%), sabinene (3.24%), beta-pinen (3.34%), beta-myrcene (3.23%) , cymene (3.68%), alpha-limonene (2.82%), eucalyptol (1,8-cineo (4.71%), 1,3-benzodioxole, 5-(2-, (3.68%) were identified. The antimicrobial activity of different extract was tested against human and plant pathogenic bacteria. Hexane-ethyl acetate extract showed significant role on inhibiting almost all tested pathogenic organisms. Using histochemical reagents such as Phloroglucinol-HCl, Dragendorffreagent was used for the localization of lignin and alkaloids respectively. Mangifera indica showed 100% larvicide activity. The addition of various concentrations of hexane-ethyl acetate extract of Mangifera indica on the L929 cell lines showed cytotoxic activity.</description><identifier>EISSN: 0975-8232</identifier><language>eng</language><subject>Mangifera indica</subject><ispartof>International journal of pharmaceutical sciences and research, 2013-02, Vol.4 (2), p.819-819</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids></links><search><creatorcontrib>Helen, P A Mary</creatorcontrib><creatorcontrib>Aswathy, M R</creatorcontrib><creatorcontrib>Rathi, K G Deepthi R Mol</creatorcontrib><creatorcontrib>Joseph, J Jaison</creatorcontrib><creatorcontrib>Sree, S Jaya</creatorcontrib><title>PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)</title><title>International journal of pharmaceutical sciences and research</title><description>About 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. Ten constituents from 10 peaks were identified. Terpinyl acetate (5.80%) and phytol isomer (5.12%) are as the major constituents and the minor constituents like oxirane (3.57%), sabinene (3.24%), beta-pinen (3.34%), beta-myrcene (3.23%) , cymene (3.68%), alpha-limonene (2.82%), eucalyptol (1,8-cineo (4.71%), 1,3-benzodioxole, 5-(2-, (3.68%) were identified. The antimicrobial activity of different extract was tested against human and plant pathogenic bacteria. Hexane-ethyl acetate extract showed significant role on inhibiting almost all tested pathogenic organisms. Using histochemical reagents such as Phloroglucinol-HCl, Dragendorffreagent was used for the localization of lignin and alkaloids respectively. Mangifera indica showed 100% larvicide activity. The addition of various concentrations of hexane-ethyl acetate extract of Mangifera indica on the L929 cell lines showed cytotoxic activity.</description><subject>Mangifera indica</subject><issn>0975-8232</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqVS80KgkAYXIIgKd9hj3UI1KXS48e25qKuoV-Sp5CwKCyrzfdvg16ggWF-mBkQywlWi7nvMW9EbK2vjsHSc12fWeS8jSrMeCRSySGhoCCpClkYszZEUyoucgocZSmxollIEwEhFXvMTfnNKaiNDEUOVKq1OdBpnCHiLs4UpLSEXMYwm5DhqW51Y_90TKahQB7NH6_u2Tf6fbhd9LFp2_redL0-uCwIAtfzmcP-mH4A2FBBIw</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Helen, P A Mary</creator><creator>Aswathy, M R</creator><creator>Rathi, K G Deepthi R Mol</creator><creator>Joseph, J Jaison</creator><creator>Sree, S Jaya</creator><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20130201</creationdate><title>PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)</title><author>Helen, P A Mary ; Aswathy, M R ; Rathi, K G Deepthi R Mol ; Joseph, J Jaison ; Sree, S Jaya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_13999128303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Mangifera indica</topic><toplevel>online_resources</toplevel><creatorcontrib>Helen, P A Mary</creatorcontrib><creatorcontrib>Aswathy, M R</creatorcontrib><creatorcontrib>Rathi, K G Deepthi R Mol</creatorcontrib><creatorcontrib>Joseph, J Jaison</creatorcontrib><creatorcontrib>Sree, S Jaya</creatorcontrib><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>International journal of pharmaceutical sciences and research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Helen, P A Mary</au><au>Aswathy, M R</au><au>Rathi, K G Deepthi R Mol</au><au>Joseph, J Jaison</au><au>Sree, S Jaya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)</atitle><jtitle>International journal of pharmaceutical sciences and research</jtitle><date>2013-02-01</date><risdate>2013</risdate><volume>4</volume><issue>2</issue><spage>819</spage><epage>819</epage><pages>819-819</pages><eissn>0975-8232</eissn><abstract>About 6 extract (methanol, acetone, hexane, ethyl acetate, hexane-ethyl acetate, aqueous extraction) from the leaves of Mangifera indica was extracted. Hexane-ethyl acetate was characterized by Gas Chromatography- Mass Spectroscopy. Ten constituents from 10 peaks were identified. Terpinyl acetate (5.80%) and phytol isomer (5.12%) are as the major constituents and the minor constituents like oxirane (3.57%), sabinene (3.24%), beta-pinen (3.34%), beta-myrcene (3.23%) , cymene (3.68%), alpha-limonene (2.82%), eucalyptol (1,8-cineo (4.71%), 1,3-benzodioxole, 5-(2-, (3.68%) were identified. The antimicrobial activity of different extract was tested against human and plant pathogenic bacteria. Hexane-ethyl acetate extract showed significant role on inhibiting almost all tested pathogenic organisms. Using histochemical reagents such as Phloroglucinol-HCl, Dragendorffreagent was used for the localization of lignin and alkaloids respectively. Mangifera indica showed 100% larvicide activity. The addition of various concentrations of hexane-ethyl acetate extract of Mangifera indica on the L929 cell lines showed cytotoxic activity.</abstract></addata></record>
fulltext fulltext
identifier EISSN: 0975-8232
ispartof International journal of pharmaceutical sciences and research, 2013-02, Vol.4 (2), p.819-819
issn 0975-8232
language eng
recordid cdi_proquest_miscellaneous_1399912830
source EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Mangifera indica
title PHYTOCHEMICAL ANALYSIS AND ANTICANCER ACTIVITY OF LEAF EXTRACT OF MANGIFERA INDICA (KOTTTUKONAM VARIKA)
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-12T01%3A37%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=PHYTOCHEMICAL%20ANALYSIS%20AND%20ANTICANCER%20ACTIVITY%20OF%20LEAF%20EXTRACT%20OF%20MANGIFERA%20INDICA%20(KOTTTUKONAM%20VARIKA)&rft.jtitle=International%20journal%20of%20pharmaceutical%20sciences%20and%20research&rft.au=Helen,%20P%20A%20Mary&rft.date=2013-02-01&rft.volume=4&rft.issue=2&rft.spage=819&rft.epage=819&rft.pages=819-819&rft.eissn=0975-8232&rft_id=info:doi/&rft_dat=%3Cproquest%3E1399912830%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1399912830&rft_id=info:pmid/&rfr_iscdi=true