Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system

Aim In this study, we investigated the regulatory network of the key and rate‐limiting enzyme of cholesterol biosynthetic pathway, the 3‐hydroxy 3‐methylglutaryl coenzyme A reductase (HMGR) in different brain regions, to add new insight about lipid metabolism and physiology in the central nervous sy...

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Veröffentlicht in:	Acta Physiologica 2012-09, Vol.206 (1), p.62-71
Hauptverfasser:	Segatto, M., Trapani, L., Lecis, C., Pallottini, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain - enzymology Brain - metabolism central nervous system Cholesterol Cholesterol - biosynthesis Enzymes Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Gene Expression Regulation, Enzymologic - physiology HMG-CoA reductase Hydroxymethylglutaryl CoA Reductases - genetics Hydroxymethylglutaryl CoA Reductases - metabolism Male Nervous system Rats Rats, Wistar Regulation Rodents Vertebrates: anatomy and physiology, studies on body, several organs or systems
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