Lack of Independent Significance of a Close (<1 mm) Circumferential Resection Margin Involvement in Esophageal and Junctional Cancer

Background For rectal cancer, an involved circumferential resection margin (CRM), defined as tumor cells within 1 mm of the CRM, is of established prognostic significance. This definition for the esophagus, however, is controversial, with the UK Royal College of Pathologists (RCP) recommending the 1...

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