Genetic variability in copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with Alzheimer's disease in a Chinese population

Previous experiments demonstrated that transgenic mice carrying both amyloid precursor protein and mutant ATP7B transgenes reduce amyloid plaques and diminish plasma Abeta levels. These experiments showed that a structural change of ATP7B may affect Alzheimer’s disease (AD) susceptibility. In this s...

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Veröffentlicht in:	Journal of biological regulators and homeostatic agents 2013-04, Vol.27 (2), p.319-327
Hauptverfasser:	Liu, H P, Lin, W Y, Wang, W F, Tsai, C H, Wu, W C, Chiou, M T, Shen, C P, Wu, B T, Tsai, F J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Alzheimer Disease - etiology Alzheimer Disease - genetics Asian Continental Ancestry Group - genetics Cation Transport Proteins - genetics Copper-transporting ATPases Genetic Variation Genotype Humans Polymorphism, Single Nucleotide
Online-Zugang:	Volltext
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