FasL-induced apoptosis in bovine oocytes via the Bax signal

The factor associated suicide (Fas) and its ligand (FasL) signaling is an important regulatory pathway of apoptosis in mammalian follicles. However, whether apoptosis in bovine oocytes is regulated by the Fas–FasL signaling pathway remains unknown. In this study, localization of Fas and FasL in imma...

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Veröffentlicht in:	Theriogenology 2013-08, Vol.80 (3), p.248-255
Hauptverfasser:	Li, H.-J., Wang, C.-Y., Mi, Y., Du, C.-G., Cao, G.-F., Sun, X.-C., Liu, D.-J., Shorgan, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annexin A5 Apoptosis Bax bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - metabolism Bovine oocytes Cattle Cumulus Cells - metabolism Fas Fas Ligand Protein - genetics Fas Ligand Protein - metabolism FasL Female fluorescent antibody technique Gene Expression Regulation In Situ Nick-End Labeling oocytes Oocytes - physiology Protein Transport Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism quantitative polymerase chain reaction RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction - physiology Staining and Labeling suicide uridine
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