π-Allyltricarbonyliron lactone complexes in synthesis: application to the synthesis of the β-lactam antibiotic (+)-thienamycin

Synthesis of an enantiomerically pure beta -lactam intermediate used in the preparation of the antibiotic (+)-thienamycin is described, by suitable elaboration of a functionalised pi -allytricarbonyliron complex.

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Veröffentlicht in:Journal of the Chemical Society. Chemical communications 1984 (8), p.494-496
Hauptverfasser: HODGSON, S. T, HOLLINSHEAD, D. M, LEY, S. V
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container_end_page 496
container_issue 8
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container_title Journal of the Chemical Society. Chemical communications
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creator HODGSON, S. T
HOLLINSHEAD, D. M
LEY, S. V
description Synthesis of an enantiomerically pure beta -lactam intermediate used in the preparation of the antibiotic (+)-thienamycin is described, by suitable elaboration of a functionalised pi -allytricarbonyliron complex.
doi_str_mv 10.1039/C39840000494
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source Royal Society of Chemistry Journals Archive (1841-2007)
subjects Chemistry
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with only one n hetero atom and condensed derivatives
Organic chemistry
peptide synthesis
Preparations and properties
thienamycin
title π-Allyltricarbonyliron lactone complexes in synthesis: application to the synthesis of the β-lactam antibiotic (+)-thienamycin
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