Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban

The new oral anticoagulants dabigatran etexilate (Pradaxa), rivaroxaban (Xarelto), and apixaban (Eliquis) have predictable pharmacokinetic and pharmacodynamic profiles and are alternatives to warfarin. However, many physicians are wary of these drugs, since there is limited evidence on how to manage...

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Veröffentlicht in:	Cleveland Clinic journal of medicine 2013-07, Vol.80 (7), p.443-451
Hauptverfasser:	Fawole, Adewale, Daw, Hamed A, Crowther, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticoagulants - adverse effects Anticoagulants - pharmacokinetics Benzimidazoles - adverse effects Benzimidazoles - pharmacokinetics beta-Alanine - adverse effects beta-Alanine - analogs & derivatives beta-Alanine - pharmacokinetics Blood Coagulation Tests Dabigatran Drug Monitoring Hemorrhage - chemically induced Hemorrhage - prevention & control Hemorrhage - therapy Hemostatic Techniques Humans Morpholines - adverse effects Morpholines - pharmacokinetics Perioperative Care Pyrazoles - adverse effects Pyrazoles - pharmacokinetics Pyridones - adverse effects Pyridones - pharmacokinetics Rivaroxaban Thiophenes - adverse effects Thiophenes - pharmacokinetics
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