Therapy of Ulcerated Hemangiomas
Background: Cutaneous ulceration is the most common complication of infantile hemangiomas (IHs) seen in a pediatric dermatology practice. Objective: The most effective treatments in our experience are compared to those in the current literature. Methods: The study was a retrospective chart review of...
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| Veröffentlicht in: | Journal of Cutaneous Medicine and Surgery 2013-07, Vol.17 (4), p.233-242 |
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| container_title | Journal of Cutaneous Medicine and Surgery |
| container_volume | 17 |
| creator | McCuaig, Catherine C. Cohen, Lynn Powell, Julie Hatami, Afshin Marcoux, Danielle Maari, Catherine Caouette-Laberge, Louise Bortoluzzi, Patricia Ondrejchak, Sandra Dubois, Josée |
| description | Background:
Cutaneous ulceration is the most common complication of infantile hemangiomas (IHs) seen in a pediatric dermatology practice.
Objective:
The most effective treatments in our experience are compared to those in the current literature.
Methods:
The study was a retrospective chart review of therapy of 169 ulcerated IHs at a tertiary care pediatric hospital and a literature review.
Results:
Combination therapy was the rule. Local wound care was required in all, pain management in 72%, pulsed dye laser in 42%, infection control in 38%, diminution of the hemangioma through systemic therapy in 36%, and suppression of bleeding in 2%.
Limitations:
A retrospective review compared to a case-control study has inherent bias. In addition, our cases were all at a tertiary referral center.
Conclusion:
All ulcerated IHs benefit from local barrier creams or dressings. Pulsed dye laser, antibiotics, topical morphine 0.1% in hydrogel, topical becaplermin, and, most importantly, systemic therapy (especially propranolol) to reduce the hemangioma may be useful. |
| doi_str_mv | 10.2310/7750.2012.12037 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1393815171</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.2310_7750.2012.12037</sage_id><sourcerecordid>1393815171</sourcerecordid><originalsourceid>FETCH-LOGICAL-c388t-c25bd4afc62a792204000f437162541c1f77addd17a60d601350993bc810777b3</originalsourceid><addsrcrecordid>eNp1kM9LwzAUx4MoTqdnb1Lw4sFu7-VH0x5lqBMGXrZzSJN0brTrTNbD_ntTN0UET_kSPu_7Hh9CbhBGlCGMpRQxAdIRUmDyhFxghiKVCMVpzPEv5VLwAbkMYQ0AiIKfkwFlOYpCiAuSzN-d19t90lbJojYx75xNpq7Rm-WqbXS4ImeVroO7Pr5Dsnh-mk-m6ezt5XXyOEsNy_NdaqgoLdeVyaiWBaXA47aKM4kZFRwNVlJqay1KnYHNAJmAomClyRGklCUbkvtD79a3H50LO9WsgnF1rTeu7YJCVvRHo8SI3v1B123nN_E6hZwKATkFGqnxgTK-DcG7Sm39qtF-rxBUL0_18lQvT33JixO3x96ubJz94b9tReDhAAS9dL-W_tP3CS0Oci4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1425508202</pqid></control><display><type>article</type><title>Therapy of Ulcerated Hemangiomas</title><source>MEDLINE</source><source>SAGE Complete A-Z List</source><creator>McCuaig, Catherine C. ; Cohen, Lynn ; Powell, Julie ; Hatami, Afshin ; Marcoux, Danielle ; Maari, Catherine ; Caouette-Laberge, Louise ; Bortoluzzi, Patricia ; Ondrejchak, Sandra ; Dubois, Josée</creator><creatorcontrib>McCuaig, Catherine C. ; Cohen, Lynn ; Powell, Julie ; Hatami, Afshin ; Marcoux, Danielle ; Maari, Catherine ; Caouette-Laberge, Louise ; Bortoluzzi, Patricia ; Ondrejchak, Sandra ; Dubois, Josée</creatorcontrib><description>Background:
Cutaneous ulceration is the most common complication of infantile hemangiomas (IHs) seen in a pediatric dermatology practice.
Objective:
The most effective treatments in our experience are compared to those in the current literature.
Methods:
The study was a retrospective chart review of therapy of 169 ulcerated IHs at a tertiary care pediatric hospital and a literature review.
Results:
Combination therapy was the rule. Local wound care was required in all, pain management in 72%, pulsed dye laser in 42%, infection control in 38%, diminution of the hemangioma through systemic therapy in 36%, and suppression of bleeding in 2%.
Limitations:
A retrospective review compared to a case-control study has inherent bias. In addition, our cases were all at a tertiary referral center.
Conclusion:
All ulcerated IHs benefit from local barrier creams or dressings. Pulsed dye laser, antibiotics, topical morphine 0.1% in hydrogel, topical becaplermin, and, most importantly, systemic therapy (especially propranolol) to reduce the hemangioma may be useful.</description><identifier>ISSN: 1203-4754</identifier><identifier>EISSN: 1615-7109</identifier><identifier>DOI: 10.2310/7750.2012.12037</identifier><identifier>PMID: 23815955</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Hemangioma - complications ; Hemangioma - therapy ; Humans ; Medical treatment ; Pain management ; Skin diseases ; Skin Neoplasms - complications ; Skin Neoplasms - therapy ; Skin Ulcer - etiology ; Skin Ulcer - therapy ; Wound healing</subject><ispartof>Journal of Cutaneous Medicine and Surgery, 2013-07, Vol.17 (4), p.233-242</ispartof><rights>2013 Canadian Dermatology Association</rights><rights>Copyright Decker Periodicals, Inc. Jul/Aug 2013</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-c25bd4afc62a792204000f437162541c1f77addd17a60d601350993bc810777b3</citedby><cites>FETCH-LOGICAL-c388t-c25bd4afc62a792204000f437162541c1f77addd17a60d601350993bc810777b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.2310/7750.2012.12037$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.2310/7750.2012.12037$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>313,314,780,784,792,21819,27922,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23815955$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>McCuaig, Catherine C.</creatorcontrib><creatorcontrib>Cohen, Lynn</creatorcontrib><creatorcontrib>Powell, Julie</creatorcontrib><creatorcontrib>Hatami, Afshin</creatorcontrib><creatorcontrib>Marcoux, Danielle</creatorcontrib><creatorcontrib>Maari, Catherine</creatorcontrib><creatorcontrib>Caouette-Laberge, Louise</creatorcontrib><creatorcontrib>Bortoluzzi, Patricia</creatorcontrib><creatorcontrib>Ondrejchak, Sandra</creatorcontrib><creatorcontrib>Dubois, Josée</creatorcontrib><title>Therapy of Ulcerated Hemangiomas</title><title>Journal of Cutaneous Medicine and Surgery</title><addtitle>J Cutan Med Surg</addtitle><description>Background:
Cutaneous ulceration is the most common complication of infantile hemangiomas (IHs) seen in a pediatric dermatology practice.
Objective:
The most effective treatments in our experience are compared to those in the current literature.
Methods:
The study was a retrospective chart review of therapy of 169 ulcerated IHs at a tertiary care pediatric hospital and a literature review.
Results:
Combination therapy was the rule. Local wound care was required in all, pain management in 72%, pulsed dye laser in 42%, infection control in 38%, diminution of the hemangioma through systemic therapy in 36%, and suppression of bleeding in 2%.
Limitations:
A retrospective review compared to a case-control study has inherent bias. In addition, our cases were all at a tertiary referral center.
Conclusion:
All ulcerated IHs benefit from local barrier creams or dressings. Pulsed dye laser, antibiotics, topical morphine 0.1% in hydrogel, topical becaplermin, and, most importantly, systemic therapy (especially propranolol) to reduce the hemangioma may be useful.</description><subject>Hemangioma - complications</subject><subject>Hemangioma - therapy</subject><subject>Humans</subject><subject>Medical treatment</subject><subject>Pain management</subject><subject>Skin diseases</subject><subject>Skin Neoplasms - complications</subject><subject>Skin Neoplasms - therapy</subject><subject>Skin Ulcer - etiology</subject><subject>Skin Ulcer - therapy</subject><subject>Wound healing</subject><issn>1203-4754</issn><issn>1615-7109</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM9LwzAUx4MoTqdnb1Lw4sFu7-VH0x5lqBMGXrZzSJN0brTrTNbD_ntTN0UET_kSPu_7Hh9CbhBGlCGMpRQxAdIRUmDyhFxghiKVCMVpzPEv5VLwAbkMYQ0AiIKfkwFlOYpCiAuSzN-d19t90lbJojYx75xNpq7Rm-WqbXS4ImeVroO7Pr5Dsnh-mk-m6ezt5XXyOEsNy_NdaqgoLdeVyaiWBaXA47aKM4kZFRwNVlJqay1KnYHNAJmAomClyRGklCUbkvtD79a3H50LO9WsgnF1rTeu7YJCVvRHo8SI3v1B123nN_E6hZwKATkFGqnxgTK-DcG7Sm39qtF-rxBUL0_18lQvT33JixO3x96ubJz94b9tReDhAAS9dL-W_tP3CS0Oci4</recordid><startdate>20130701</startdate><enddate>20130701</enddate><creator>McCuaig, Catherine C.</creator><creator>Cohen, Lynn</creator><creator>Powell, Julie</creator><creator>Hatami, Afshin</creator><creator>Marcoux, Danielle</creator><creator>Maari, Catherine</creator><creator>Caouette-Laberge, Louise</creator><creator>Bortoluzzi, Patricia</creator><creator>Ondrejchak, Sandra</creator><creator>Dubois, Josée</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20130701</creationdate><title>Therapy of Ulcerated Hemangiomas</title><author>McCuaig, Catherine C. ; Cohen, Lynn ; Powell, Julie ; Hatami, Afshin ; Marcoux, Danielle ; Maari, Catherine ; Caouette-Laberge, Louise ; Bortoluzzi, Patricia ; Ondrejchak, Sandra ; Dubois, Josée</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-c25bd4afc62a792204000f437162541c1f77addd17a60d601350993bc810777b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Hemangioma - complications</topic><topic>Hemangioma - therapy</topic><topic>Humans</topic><topic>Medical treatment</topic><topic>Pain management</topic><topic>Skin diseases</topic><topic>Skin Neoplasms - complications</topic><topic>Skin Neoplasms - therapy</topic><topic>Skin Ulcer - etiology</topic><topic>Skin Ulcer - therapy</topic><topic>Wound healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>McCuaig, Catherine C.</creatorcontrib><creatorcontrib>Cohen, Lynn</creatorcontrib><creatorcontrib>Powell, Julie</creatorcontrib><creatorcontrib>Hatami, Afshin</creatorcontrib><creatorcontrib>Marcoux, Danielle</creatorcontrib><creatorcontrib>Maari, Catherine</creatorcontrib><creatorcontrib>Caouette-Laberge, Louise</creatorcontrib><creatorcontrib>Bortoluzzi, Patricia</creatorcontrib><creatorcontrib>Ondrejchak, Sandra</creatorcontrib><creatorcontrib>Dubois, Josée</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of Cutaneous Medicine and Surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>McCuaig, Catherine C.</au><au>Cohen, Lynn</au><au>Powell, Julie</au><au>Hatami, Afshin</au><au>Marcoux, Danielle</au><au>Maari, Catherine</au><au>Caouette-Laberge, Louise</au><au>Bortoluzzi, Patricia</au><au>Ondrejchak, Sandra</au><au>Dubois, Josée</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Therapy of Ulcerated Hemangiomas</atitle><jtitle>Journal of Cutaneous Medicine and Surgery</jtitle><addtitle>J Cutan Med Surg</addtitle><date>2013-07-01</date><risdate>2013</risdate><volume>17</volume><issue>4</issue><spage>233</spage><epage>242</epage><pages>233-242</pages><issn>1203-4754</issn><eissn>1615-7109</eissn><abstract>Background:
Cutaneous ulceration is the most common complication of infantile hemangiomas (IHs) seen in a pediatric dermatology practice.
Objective:
The most effective treatments in our experience are compared to those in the current literature.
Methods:
The study was a retrospective chart review of therapy of 169 ulcerated IHs at a tertiary care pediatric hospital and a literature review.
Results:
Combination therapy was the rule. Local wound care was required in all, pain management in 72%, pulsed dye laser in 42%, infection control in 38%, diminution of the hemangioma through systemic therapy in 36%, and suppression of bleeding in 2%.
Limitations:
A retrospective review compared to a case-control study has inherent bias. In addition, our cases were all at a tertiary referral center.
Conclusion:
All ulcerated IHs benefit from local barrier creams or dressings. Pulsed dye laser, antibiotics, topical morphine 0.1% in hydrogel, topical becaplermin, and, most importantly, systemic therapy (especially propranolol) to reduce the hemangioma may be useful.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>23815955</pmid><doi>10.2310/7750.2012.12037</doi><tpages>10</tpages></addata></record> |
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| ispartof | Journal of Cutaneous Medicine and Surgery, 2013-07, Vol.17 (4), p.233-242 |
| issn | 1203-4754 1615-7109 |
| language | eng |
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| source | MEDLINE; SAGE Complete A-Z List |
| subjects | Hemangioma - complications Hemangioma - therapy Humans Medical treatment Pain management Skin diseases Skin Neoplasms - complications Skin Neoplasms - therapy Skin Ulcer - etiology Skin Ulcer - therapy Wound healing |
| title | Therapy of Ulcerated Hemangiomas |
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