Guinea pig line 10 hepatocarcinoma model: characterization of monoclonal antibody and in vivo effect of unconjugated antibody and antibody conjugated to diphtheria toxin A chain

Monoclonal antibodies were raised against the guinea pig line 10 (L10) hepatocarcinoma, and an IgG1-producing hybridoma (D3) was selected for further study. D3 is a true monoclonal antibody as demonstrated by two-dimensional gel electrophoresis. Radioimmunoassays on live cells revealed no cross-reac...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1983-09, Vol.43 (9), p.4420-4428
Hauptverfasser:	BERNHARD, M. I, FOON, K. A, OELTMANN, T. N, KEY, M. E, HWANG, K. M, CLARKE, G. C, CHRISTENSEN, W. L, HOYER, L. C, HANNA, M. G. JR, OLDHAM, R. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - immunology Antibodies, Monoclonal - immunology Antigen-Antibody Complex Antigens, Neoplasm - analysis Antigens, Surface - analysis Biological and medical sciences Cell Line Diphtheria Toxin Female Guinea Pigs Immunoelectrophoresis Immunoenzyme Techniques Immunomodulators Liver - immunology Liver Neoplasms, Experimental - immunology Medical sciences Mice Peptide Fragments Pharmacology. Drug treatments Radioimmunoassay
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