The periodic loss of metabolically unstable DNA during replication of chromosomal DNA of CHO cells

The fate of 3H-thymidine incorporated into newly synthesized DNA of CHO cells was analyzed by either the estimation of the incorporated radioactivity per cell or sedimentation in alkaline sucrose gradient. Under conditions in which DNA synthesis proceeded continuously, of incorporated radioactivity...

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Veröffentlicht in:	Biochemical and biophysical research communications 1984-03, Vol.119 (3), p.920-925
Hauptverfasser:	Masuda, Michiyoshi, Isiglo, Kimio, Yamoka, Hideki, Matsumoto, Takafumi, Takahashi, Manabu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cricetinae Cricetulus DNA - genetics DNA - isolation & purification DNA - metabolism DNA Replication - drug effects Female Hydroxyurea - toxicity Kinetics Ovary
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