Non-induction of Dominant Lethal Mutations in Mice Fed Gamma-irradiated Glucose

The application of ionizing radiation for the preservation of food and food components has come into recognition with the advent of nuclear technology. The present investigation was undertaken to evaluate the mutagenicity of irradiated glucose by the dominant lethal test in male mice. There were no...

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Veröffentlicht in:	International journal of radiation biology 1982-01, Vol.42 (5), p.559-563
Hauptverfasser:	Varma, Manju Bala, Nandan, S. Devaki, Rao, K.P., Rao, M. Sanjeeva
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cobalt Radioisotopes Dietary Carbohydrates - radiation effects Food Irradiation - adverse effects Gamma Rays Genes, Dominant Genes, Lethal Glucose - radiation effects Male Mice Mutation
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container_end_page	563
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container_title	International journal of radiation biology
container_volume	42
creator	Varma, Manju Bala Nandan, S. Devaki Rao, K.P. Rao, M. Sanjeeva
description	The application of ionizing radiation for the preservation of food and food components has come into recognition with the advent of nuclear technology. The present investigation was undertaken to evaluate the mutagenicity of irradiated glucose by the dominant lethal test in male mice. There were no significant differences in total implantation and survival rates between control and treated groups in post-meiotic and meiotic stages of spermatogenesis. The results obtained in the long-term studies with freshly irradiated glucose and stored irradiated glucose also revealed no variation in total implantation and survival rates between control and treated groups. The data clearly indicate the inability of irradiated glucose to induce dominant lethal mutations either by short- or long-term feeding.
doi_str_mv	10.1080/09553008214551491
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source	MEDLINE; Taylor & Francis:Master (3349 titles); Taylor & Francis Medical Library - CRKN
subjects	Animals Cobalt Radioisotopes Dietary Carbohydrates - radiation effects Food Irradiation - adverse effects Gamma Rays Genes, Dominant Genes, Lethal Glucose - radiation effects Male Mice Mutation
title	Non-induction of Dominant Lethal Mutations in Mice Fed Gamma-irradiated Glucose
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