Effects of ribavirin on red blood cells

Man and rhesus monkey may develop anemia during treatment with the broad-spectrum antiviral ribavirin (1-β-ribofuranosyl-1,2,4-triazole-3-carboxamide). To assess whether the anemia is due to decreased production of erythrocytes, increased destruction, or a combination of both factors, the transport...

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Veröffentlicht in:	Toxicology and applied pharmacology 1984-06, Vol.74 (2), p.155-162
Hauptverfasser:	Canonico, Peter G., Kastello, Michael D., Spears, Charles T., Brown, James R., Jackson, Edwin A., Jenkins, D.Erin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Survival - drug effects Erythrocyte Count Erythrocytes - drug effects Erythrocytes - metabolism Erythrocytes - physiology Humans In Vitro Techniques Isoflurophate Macaca mulatta Male Osmotic Fragility - drug effects Rats Rats, Inbred Strains Ribavirin - blood Ribavirin - toxicity Ribonucleosides - toxicity
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