A general probabilistic model of carcinogenesis: analysis of experimental urinary bladder cancer

A theoretical model of two-stage carcinogenesis has been hypothesized. Variables that are modeled include the populations of normal, initiated, and transformed cells; mitotic rates of these cells; hyperplasia; and the probabilities of cell initiation and transformation during replication. The size o...

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Veröffentlicht in:	Carcinogenesis (New York) 1984-04, Vol.5 (4), p.437-445
Hauptverfasser:	Greenfield, Robert E., Ellwein, Leon B., Cohen, Samuel M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Cell Cycle Cell Transformation, Neoplastic Chemical agents FANFT Mathematics Medical sciences Mitosis Models, Biological Neoplasms, Experimental - physiopathology Probability Rats Saccharin Tumors Urinary Bladder Neoplasms - chemically induced Urinary Bladder Neoplasms - physiopathology
Online-Zugang:	Volltext
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