5'-Amino-5'-deoxythymidine: Topical Therapeutic Efficacy in Ocular Herpes and Systemic Teratogenic and Toxicity Studies

Abstract AdThd (5'-amino-5'-deoxythymidine) is a highly soluble new antiviral drug specifically activated by herpes simplex viral thymidine kinase. Ten and fifteen percent AdThd eye drops were significantly better than placebo in therapy of herpetic keratouveitis in rabbits and the slope o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1982-05, Vol.170 (1), p.1-7
Hauptverfasser:	Pavan-Langston, D., Park, N. H., Lass, J., Papale, J., Albert, D. M., Lin, T., Prusoff, W. H., Percy, D. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Animals Animals, Newborn Dideoxynucleosides Drug Evaluation, Preclinical Eye - pathology herpes simplex virus Idoxuridine - toxicity Keratitis, Dendritic - drug therapy Male Mice Rabbits Teratogens Thymidine - administration & dosage Thymidine - analogs & derivatives Thymidine - therapeutic use Thymidine - toxicity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!