Ethanol consumption and blood pressure
Chronic ethanol consumption consistently resulted in mild hypertension in the male Wistar rats used in the present study. The ethanol-treated animals also have reduced 24-hour urinary output and significant sodium retention when compared to the controls. Total plasma volume was estimated using the t...
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| Veröffentlicht in: | Life sciences (1973) 1983-11, Vol.33 (20), p.1965-1973 |
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| container_end_page | 1973 |
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| container_issue | 20 |
| container_start_page | 1965 |
| container_title | Life sciences (1973) |
| container_volume | 33 |
| creator | Chan, Thomas C.K. Sutter, Morley C. |
| description | Chronic ethanol consumption consistently resulted in mild hypertension in the male Wistar rats used in the present study. The ethanol-treated animals also have reduced 24-hour urinary output and significant sodium retention when compared to the controls. Total plasma volume was estimated using the technique of indicator dilution, and an increase of 20% was observed in the ethanol-treated animals. Vascular smooth muscle resposiveness to noradrenaline in vitro was not different between the two groups of animals. Therefore the blood pressure elevation in the ethanol-treated animals seems to be associated with sodium retention and plasma volume expansion, and probably is unrelated to altered vascular responsiveness. |
| doi_str_mv | 10.1016/0024-3205(83)90734-8 |
| format | Article |
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The ethanol-treated animals also have reduced 24-hour urinary output and significant sodium retention when compared to the controls. Total plasma volume was estimated using the technique of indicator dilution, and an increase of 20% was observed in the ethanol-treated animals. Vascular smooth muscle resposiveness to noradrenaline in vitro was not different between the two groups of animals. Therefore the blood pressure elevation in the ethanol-treated animals seems to be associated with sodium retention and plasma volume expansion, and probably is unrelated to altered vascular responsiveness.</description><identifier>ISSN: 0024-3205</identifier><identifier>EISSN: 1879-0631</identifier><identifier>DOI: 10.1016/0024-3205(83)90734-8</identifier><identifier>PMID: 6685805</identifier><identifier>CODEN: LIFSAK</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>Alcoholism - complications ; Alcoholism - physiopathology ; Alcoholism and acute alcohol poisoning ; Animals ; Biological and medical sciences ; Diuresis ; Eating ; Humans ; Hypertension - etiology ; Magnesium - urine ; Male ; Medical sciences ; Muscle Contraction - drug effects ; Muscle, Smooth, Vascular - physiology ; Norepinephrine - pharmacology ; Plasma Volume ; Rats ; Rats, Inbred Strains ; Sodium - urine ; Toxicology</subject><ispartof>Life sciences (1973), 1983-11, Vol.33 (20), p.1965-1973</ispartof><rights>1983</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-117cd8eed795ac6472a949dbb80108ac0275d794517347007f803abfb7ee52963</citedby><cites>FETCH-LOGICAL-c417t-117cd8eed795ac6472a949dbb80108ac0275d794517347007f803abfb7ee52963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0024320583907348$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9640015$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6685805$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, Thomas C.K.</creatorcontrib><creatorcontrib>Sutter, Morley C.</creatorcontrib><title>Ethanol consumption and blood pressure</title><title>Life sciences (1973)</title><addtitle>Life Sci</addtitle><description>Chronic ethanol consumption consistently resulted in mild hypertension in the male Wistar rats used in the present study. 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Therefore the blood pressure elevation in the ethanol-treated animals seems to be associated with sodium retention and plasma volume expansion, and probably is unrelated to altered vascular responsiveness.</description><subject>Alcoholism - complications</subject><subject>Alcoholism - physiopathology</subject><subject>Alcoholism and acute alcohol poisoning</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Diuresis</subject><subject>Eating</subject><subject>Humans</subject><subject>Hypertension - etiology</subject><subject>Magnesium - urine</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle Contraction - drug effects</subject><subject>Muscle, Smooth, Vascular - physiology</subject><subject>Norepinephrine - pharmacology</subject><subject>Plasma Volume</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Sodium - urine</subject><subject>Toxicology</subject><issn>0024-3205</issn><issn>1879-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLxDAUhYMo4zj6DxS6ENFF9aZpHt0IMowPGHCj65Cmt1hpm5q0gv_e1imzdHUX5zuHcw8h5xRuKVBxB5CkMUuAXyt2k4FkaawOyJIqmcUgGD0kyz1yTE5C-AQAziVbkIUQiivgS3K16T9M6-rIujYMTddXro1MW0R57VwRdR5DGDyekqPS1AHP5rsi74-bt_VzvH19elk_bGObUtnHlEpbKMRCZtxYkcrEZGlW5LkCCspYSCQftZTTsa0EkKUCZvIyl4g8yQRbkatdbufd14Ch100VLNa1adENQVOmmBSJGsF0B1rvQvBY6s5XjfE_moKe5tHT73r6XSum_-bRk-1izh_yBou9ad5j1C9n3QRr6tKb1lZhj2UiBaATdr_DcNziu0Kvg62wtVhUHm2vC1f93-MXa15-nw</recordid><startdate>19831114</startdate><enddate>19831114</enddate><creator>Chan, Thomas C.K.</creator><creator>Sutter, Morley C.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>19831114</creationdate><title>Ethanol consumption and blood pressure</title><author>Chan, Thomas C.K. ; Sutter, Morley C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-117cd8eed795ac6472a949dbb80108ac0275d794517347007f803abfb7ee52963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Alcoholism - complications</topic><topic>Alcoholism - physiopathology</topic><topic>Alcoholism and acute alcohol poisoning</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Diuresis</topic><topic>Eating</topic><topic>Humans</topic><topic>Hypertension - etiology</topic><topic>Magnesium - urine</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Muscle Contraction - drug effects</topic><topic>Muscle, Smooth, Vascular - physiology</topic><topic>Norepinephrine - pharmacology</topic><topic>Plasma Volume</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Sodium - urine</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chan, Thomas C.K.</creatorcontrib><creatorcontrib>Sutter, Morley C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Life sciences (1973)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Thomas C.K.</au><au>Sutter, Morley C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ethanol consumption and blood pressure</atitle><jtitle>Life sciences (1973)</jtitle><addtitle>Life Sci</addtitle><date>1983-11-14</date><risdate>1983</risdate><volume>33</volume><issue>20</issue><spage>1965</spage><epage>1973</epage><pages>1965-1973</pages><issn>0024-3205</issn><eissn>1879-0631</eissn><coden>LIFSAK</coden><abstract>Chronic ethanol consumption consistently resulted in mild hypertension in the male Wistar rats used in the present study. The ethanol-treated animals also have reduced 24-hour urinary output and significant sodium retention when compared to the controls. Total plasma volume was estimated using the technique of indicator dilution, and an increase of 20% was observed in the ethanol-treated animals. Vascular smooth muscle resposiveness to noradrenaline in vitro was not different between the two groups of animals. Therefore the blood pressure elevation in the ethanol-treated animals seems to be associated with sodium retention and plasma volume expansion, and probably is unrelated to altered vascular responsiveness.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>6685805</pmid><doi>10.1016/0024-3205(83)90734-8</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Life sciences (1973), 1983-11, Vol.33 (20), p.1965-1973 |
| issn | 0024-3205 1879-0631 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Alcoholism - complications Alcoholism - physiopathology Alcoholism and acute alcohol poisoning Animals Biological and medical sciences Diuresis Eating Humans Hypertension - etiology Magnesium - urine Male Medical sciences Muscle Contraction - drug effects Muscle, Smooth, Vascular - physiology Norepinephrine - pharmacology Plasma Volume Rats Rats, Inbred Strains Sodium - urine Toxicology |
| title | Ethanol consumption and blood pressure |
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