Neurogenic vasoconstriction of cat cerebral and femoral arteries
1. 1. Segments of cat posterior communicating artery and femoral artery submitted to field electrical stimulation showed frequency-dependent contractile responses which were decreased by tetrodotoxin, bretylium, and reserpine pretreatment. Phentolamine could only reduce the response of femoral arter...
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| Veröffentlicht in: | General pharmacology 1983, Vol.14 (3), p.355-360 |
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| container_title | General pharmacology |
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| creator | Salaíces, M. Marín, J. Marco, E.J. Conde, M.V. Gómez, B. Lluch, S. |
| description | 1.
1. Segments of cat posterior communicating artery and femoral artery submitted to field electrical stimulation showed frequency-dependent contractile responses which were decreased by tetrodotoxin, bretylium, and reserpine pretreatment. Phentolamine could only reduce the response of femoral artery segments. Superior cervical gangliectomy also decreased the contractions of cerebral cylinders.
2.
2. The tritium released by electrical stimulation from both kinds of vessels preloaded with [
3H]noradrenaline appeared reduced in the presence of tetrodotoxin, bretylium, and after reserpine pretreatment. It was also decreased in cerebral segments after superior cervical gangliectomy.
3.
3. These results suggest that the electrical field stimulates the sympathetic nerve endings of these vessels. |
| doi_str_mv | 10.1016/0306-3623(83)90043-5 |
| format | Article |
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1. Segments of cat posterior communicating artery and femoral artery submitted to field electrical stimulation showed frequency-dependent contractile responses which were decreased by tetrodotoxin, bretylium, and reserpine pretreatment. Phentolamine could only reduce the response of femoral artery segments. Superior cervical gangliectomy also decreased the contractions of cerebral cylinders.
2.
2. The tritium released by electrical stimulation from both kinds of vessels preloaded with [
3H]noradrenaline appeared reduced in the presence of tetrodotoxin, bretylium, and after reserpine pretreatment. It was also decreased in cerebral segments after superior cervical gangliectomy.
3.
3. These results suggest that the electrical field stimulates the sympathetic nerve endings of these vessels.</description><identifier>ISSN: 0306-3623</identifier><identifier>EISSN: 1879-0011</identifier><identifier>DOI: 10.1016/0306-3623(83)90043-5</identifier><identifier>PMID: 6873625</identifier><language>eng</language><publisher>England: Elsevier Inc</publisher><subject>Animals ; Bretylium Compounds - pharmacology ; Cats ; Cerebral Arteries - innervation ; Cerebral Arteries - physiology ; Cocaine - pharmacology ; Electric Stimulation ; Female ; Femoral Artery - innervation ; Femoral Artery - physiology ; Ganglia, Sympathetic - physiology ; Male ; Phentolamine - pharmacology ; Reserpine - pharmacology ; Tetrodotoxin - pharmacology ; Vasoconstriction</subject><ispartof>General pharmacology, 1983, Vol.14 (3), p.355-360</ispartof><rights>1983</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-ac6f1ce175ccd4a850f4143592b1a4f43cebb800d89dd3d7f5c214ee6e2c78843</citedby><cites>FETCH-LOGICAL-c388t-ac6f1ce175ccd4a850f4143592b1a4f43cebb800d89dd3d7f5c214ee6e2c78843</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6873625$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Salaíces, M.</creatorcontrib><creatorcontrib>Marín, J.</creatorcontrib><creatorcontrib>Marco, E.J.</creatorcontrib><creatorcontrib>Conde, M.V.</creatorcontrib><creatorcontrib>Gómez, B.</creatorcontrib><creatorcontrib>Lluch, S.</creatorcontrib><title>Neurogenic vasoconstriction of cat cerebral and femoral arteries</title><title>General pharmacology</title><addtitle>Gen Pharmacol</addtitle><description>1.
1. Segments of cat posterior communicating artery and femoral artery submitted to field electrical stimulation showed frequency-dependent contractile responses which were decreased by tetrodotoxin, bretylium, and reserpine pretreatment. Phentolamine could only reduce the response of femoral artery segments. Superior cervical gangliectomy also decreased the contractions of cerebral cylinders.
2.
2. The tritium released by electrical stimulation from both kinds of vessels preloaded with [
3H]noradrenaline appeared reduced in the presence of tetrodotoxin, bretylium, and after reserpine pretreatment. It was also decreased in cerebral segments after superior cervical gangliectomy.
3.
3. These results suggest that the electrical field stimulates the sympathetic nerve endings of these vessels.</description><subject>Animals</subject><subject>Bretylium Compounds - pharmacology</subject><subject>Cats</subject><subject>Cerebral Arteries - innervation</subject><subject>Cerebral Arteries - physiology</subject><subject>Cocaine - pharmacology</subject><subject>Electric Stimulation</subject><subject>Female</subject><subject>Femoral Artery - innervation</subject><subject>Femoral Artery - physiology</subject><subject>Ganglia, Sympathetic - physiology</subject><subject>Male</subject><subject>Phentolamine - pharmacology</subject><subject>Reserpine - pharmacology</subject><subject>Tetrodotoxin - pharmacology</subject><subject>Vasoconstriction</subject><issn>0306-3623</issn><issn>1879-0011</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMo67r6DxR6Ej1UkyZt04soi1-w6EXPIZ1MJNI2a9Iu-O_tfrBHTzPM-74zzEPIOaM3jLLilnJapLzI-JXk1xWlgqf5AZkyWVYppYwdkuneckxOYvymlGZ5lk3IpJDlOM6n5P4Nh-C_sHOQrHT04LvYBwe9813ibQK6TwAD1kE3ie5MYrH1mz70GBzGU3JkdRPxbFdn5PPp8WP-ki7en1_nD4sUuJR9qqGwDJCVOYARWubUCiZ4XmU108IKDljXklIjK2O4KW0OGROIBWZQSin4jFxu9y6D_xkw9qp1EbBpdId-iIpxyVlBy9EotkYIPsaAVi2Da3X4VYyqNTi1pqLWVJTkagNO5WPsYrd_qFs0-9CO1KjfbXUcn1w5DCqCww7QuIDQK-Pd_wf-AKvdfPs</recordid><startdate>1983</startdate><enddate>1983</enddate><creator>Salaíces, M.</creator><creator>Marín, J.</creator><creator>Marco, E.J.</creator><creator>Conde, M.V.</creator><creator>Gómez, B.</creator><creator>Lluch, S.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope></search><sort><creationdate>1983</creationdate><title>Neurogenic vasoconstriction of cat cerebral and femoral arteries</title><author>Salaíces, M. ; Marín, J. ; Marco, E.J. ; Conde, M.V. ; Gómez, B. ; Lluch, S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-ac6f1ce175ccd4a850f4143592b1a4f43cebb800d89dd3d7f5c214ee6e2c78843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Animals</topic><topic>Bretylium Compounds - pharmacology</topic><topic>Cats</topic><topic>Cerebral Arteries - innervation</topic><topic>Cerebral Arteries - physiology</topic><topic>Cocaine - pharmacology</topic><topic>Electric Stimulation</topic><topic>Female</topic><topic>Femoral Artery - innervation</topic><topic>Femoral Artery - physiology</topic><topic>Ganglia, Sympathetic - physiology</topic><topic>Male</topic><topic>Phentolamine - pharmacology</topic><topic>Reserpine - pharmacology</topic><topic>Tetrodotoxin - pharmacology</topic><topic>Vasoconstriction</topic><toplevel>online_resources</toplevel><creatorcontrib>Salaíces, M.</creatorcontrib><creatorcontrib>Marín, J.</creatorcontrib><creatorcontrib>Marco, E.J.</creatorcontrib><creatorcontrib>Conde, M.V.</creatorcontrib><creatorcontrib>Gómez, B.</creatorcontrib><creatorcontrib>Lluch, S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><jtitle>General pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Salaíces, M.</au><au>Marín, J.</au><au>Marco, E.J.</au><au>Conde, M.V.</au><au>Gómez, B.</au><au>Lluch, S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurogenic vasoconstriction of cat cerebral and femoral arteries</atitle><jtitle>General pharmacology</jtitle><addtitle>Gen Pharmacol</addtitle><date>1983</date><risdate>1983</risdate><volume>14</volume><issue>3</issue><spage>355</spage><epage>360</epage><pages>355-360</pages><issn>0306-3623</issn><eissn>1879-0011</eissn><abstract>1.
1. Segments of cat posterior communicating artery and femoral artery submitted to field electrical stimulation showed frequency-dependent contractile responses which were decreased by tetrodotoxin, bretylium, and reserpine pretreatment. Phentolamine could only reduce the response of femoral artery segments. Superior cervical gangliectomy also decreased the contractions of cerebral cylinders.
2.
2. The tritium released by electrical stimulation from both kinds of vessels preloaded with [
3H]noradrenaline appeared reduced in the presence of tetrodotoxin, bretylium, and after reserpine pretreatment. It was also decreased in cerebral segments after superior cervical gangliectomy.
3.
3. These results suggest that the electrical field stimulates the sympathetic nerve endings of these vessels.</abstract><cop>England</cop><pub>Elsevier Inc</pub><pmid>6873625</pmid><doi>10.1016/0306-3623(83)90043-5</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0306-3623 |
| ispartof | General pharmacology, 1983, Vol.14 (3), p.355-360 |
| issn | 0306-3623 1879-0011 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Bretylium Compounds - pharmacology Cats Cerebral Arteries - innervation Cerebral Arteries - physiology Cocaine - pharmacology Electric Stimulation Female Femoral Artery - innervation Femoral Artery - physiology Ganglia, Sympathetic - physiology Male Phentolamine - pharmacology Reserpine - pharmacology Tetrodotoxin - pharmacology Vasoconstriction |
| title | Neurogenic vasoconstriction of cat cerebral and femoral arteries |
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