CXCR7/CXCR4/CXCL12 Axis Regulates the Proliferation, Migration, Survival and Tube Formation of Choroid-Retinal Endothelial Cells

Background/Aims: Stromal cell-derived factor-1 (SDF-1) has been shown to mediate a broad range of biological processes via CXCR4, once regarded as its only receptor. CXCR7 is a recently identified receptor for SDF-1. This study aimed to investigate whether the CXCR7/CXCR4/SDF-1 axis is involved in c...

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Veröffentlicht in:	Ophthalmic research 2013-01, Vol.50 (1), p.6-12
Hauptverfasser:	Jin, Jing, Zhao, Wen-cheng, Yuan, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Blotting, Western Cell Movement - physiology Cell Proliferation Cell Survival - physiology Cells, Cultured Chemokine CXCL12 - physiology Choroid - cytology Choroidal Neovascularization - pathology Disease Models, Animal Endothelial Cells - physiology Hypoxia - metabolism Macaca mulatta Original Paper Real-Time Polymerase Chain Reaction Receptors, CXCR - physiology Receptors, CXCR4 - physiology Retina - cytology
Online-Zugang:	Volltext
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