Effect of Peripheral Arterial Disease and Race on Survival After Coronary Artery Bypass Grafting
Background Although peripheral arterial disease (PAD) is more prevalent among blacks, the effect of race on long-term survival after coronary artery bypass grafting (CABG) has not been examined in this population. Methods A retrospective cohort study was conducted of CABG patients between 1992 and 2...
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| Veröffentlicht in: | The Annals of thoracic surgery 2013-07, Vol.96 (1), p.112-118 |
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| container_title | The Annals of thoracic surgery |
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| creator | Efird, Jimmy T., PhD, MS O'Neal, Wesley T., MD O'Neal, Jason B., MD Ferguson, T. Bruce, MD Chitwood, W. Randolph, MD Kypson, Alan P., MD |
| description | Background Although peripheral arterial disease (PAD) is more prevalent among blacks, the effect of race on long-term survival after coronary artery bypass grafting (CABG) has not been examined in this population. Methods A retrospective cohort study was conducted of CABG patients between 1992 and 2011. Long-term survival was compared in patients with and without PAD and stratified by race. Hazard ratios (HR) and 95% confidence intervals were computed using a Cox regression model. Results Of 13,053 patients who underwent CABG, 1,501 (11%) had PAD, comprising 311 blacks and 1,190 whites. Median follow-up was 8.3 years. Long-term survival differed by race (no PAD: HR, 1.0; white PAD: adjusted HR, 1.5, 95% confidence interval, 1.4 to 1.6; black PAD: adjusted HR, 2.1, 95% confidence interval, 1.8 to 2.5; p < 0.0001 for trend). Conclusions Risk of death after CABG was comparatively higher among black PAD patients. This finding provides useful outcome information for surgeons and their patients. |
| doi_str_mv | 10.1016/j.athoracsur.2013.04.006 |
| format | Article |
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Bruce, MD ; Chitwood, W. Randolph, MD ; Kypson, Alan P., MD</creator><creatorcontrib>Efird, Jimmy T., PhD, MS ; O'Neal, Wesley T., MD ; O'Neal, Jason B., MD ; Ferguson, T. Bruce, MD ; Chitwood, W. Randolph, MD ; Kypson, Alan P., MD</creatorcontrib><description>Background Although peripheral arterial disease (PAD) is more prevalent among blacks, the effect of race on long-term survival after coronary artery bypass grafting (CABG) has not been examined in this population. Methods A retrospective cohort study was conducted of CABG patients between 1992 and 2011. Long-term survival was compared in patients with and without PAD and stratified by race. Hazard ratios (HR) and 95% confidence intervals were computed using a Cox regression model. Results Of 13,053 patients who underwent CABG, 1,501 (11%) had PAD, comprising 311 blacks and 1,190 whites. Median follow-up was 8.3 years. Long-term survival differed by race (no PAD: HR, 1.0; white PAD: adjusted HR, 1.5, 95% confidence interval, 1.4 to 1.6; black PAD: adjusted HR, 2.1, 95% confidence interval, 1.8 to 2.5; p < 0.0001 for trend). Conclusions Risk of death after CABG was comparatively higher among black PAD patients. This finding provides useful outcome information for surgeons and their patients.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2013.04.006</identifier><identifier>PMID: 23735717</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Angiography ; Ankle Brachial Index ; Cardiothoracic Surgery ; Confidence Intervals ; Continental Population Groups ; Coronary Artery Bypass - mortality ; Coronary Artery Disease - complications ; Coronary Artery Disease - ethnology ; Coronary Artery Disease - surgery ; Follow-Up Studies ; Humans ; Incidence ; North Carolina - epidemiology ; Peripheral Arterial Disease - complications ; Peripheral Arterial Disease - diagnosis ; Peripheral Arterial Disease - ethnology ; Postoperative Period ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; Surgery ; Survival Rate - trends ; Time Factors ; Treatment Outcome</subject><ispartof>The Annals of thoracic surgery, 2013-07, Vol.96 (1), p.112-118</ispartof><rights>The Society of Thoracic Surgeons</rights><rights>2013 The Society of Thoracic Surgeons</rights><rights>Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c495t-2c2cb44b717ceac26f87cd948502b6040f905851db30adf5c8f5bcb1b9a2a0163</citedby><cites>FETCH-LOGICAL-c495t-2c2cb44b717ceac26f87cd948502b6040f905851db30adf5c8f5bcb1b9a2a0163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23735717$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Efird, Jimmy T., PhD, MS</creatorcontrib><creatorcontrib>O'Neal, Wesley T., MD</creatorcontrib><creatorcontrib>O'Neal, Jason B., MD</creatorcontrib><creatorcontrib>Ferguson, T. Bruce, MD</creatorcontrib><creatorcontrib>Chitwood, W. Randolph, MD</creatorcontrib><creatorcontrib>Kypson, Alan P., MD</creatorcontrib><title>Effect of Peripheral Arterial Disease and Race on Survival After Coronary Artery Bypass Grafting</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Background Although peripheral arterial disease (PAD) is more prevalent among blacks, the effect of race on long-term survival after coronary artery bypass grafting (CABG) has not been examined in this population. Methods A retrospective cohort study was conducted of CABG patients between 1992 and 2011. Long-term survival was compared in patients with and without PAD and stratified by race. Hazard ratios (HR) and 95% confidence intervals were computed using a Cox regression model. Results Of 13,053 patients who underwent CABG, 1,501 (11%) had PAD, comprising 311 blacks and 1,190 whites. Median follow-up was 8.3 years. Long-term survival differed by race (no PAD: HR, 1.0; white PAD: adjusted HR, 1.5, 95% confidence interval, 1.4 to 1.6; black PAD: adjusted HR, 2.1, 95% confidence interval, 1.8 to 2.5; p < 0.0001 for trend). Conclusions Risk of death after CABG was comparatively higher among black PAD patients. This finding provides useful outcome information for surgeons and their patients.</description><subject>Angiography</subject><subject>Ankle Brachial Index</subject><subject>Cardiothoracic Surgery</subject><subject>Confidence Intervals</subject><subject>Continental Population Groups</subject><subject>Coronary Artery Bypass - mortality</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - ethnology</subject><subject>Coronary Artery Disease - surgery</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Incidence</subject><subject>North Carolina - epidemiology</subject><subject>Peripheral Arterial Disease - complications</subject><subject>Peripheral Arterial Disease - diagnosis</subject><subject>Peripheral Arterial Disease - ethnology</subject><subject>Postoperative Period</subject><subject>Proportional Hazards Models</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Surgery</subject><subject>Survival Rate - trends</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1P3DAQQK2Kqiy0f6HykUvSsR3n44IEWwpISFRAz67jjIu32Xixk5X239fRQpE4cbJHfjPjeUMIZZAzYOW3Va7HRx-0iVPIOTCRQ5EDlB_IgknJs5LL5oAsAEBkRVPJQ3IU4yqFPD1_IodcVEJWrFqQ3xfWohmpt_QnBrd5xKB7ehbGFKTLdxdRR6R66OidNkj9QO-nsHXbmbKJoksf_KDDbp-0o-e7jY6RXgZtRzf8-Uw-Wt1H_PJ8HpNfPy4ellfZze3l9fLsJjNFI8eMG27aomjTpwxqw0tbV6ZriloCb0sowDYga8m6VoDurDS1la1pWdtorpMScUxO9nU3wT9NGEe1dtFg3-sB_RQVEzWDpualSGi9R03wMQa0ahPcOo2gGKjZr1qpV79q9qugUMlvSv363GVq19j9T3wRmoDzPYBp1q3DoKJxOBjsXEieVefde7qcviliejc4o_u_uMO48lMYkkvFVOQK1P2853nNTABUAoT4Bxfvpms</recordid><startdate>20130701</startdate><enddate>20130701</enddate><creator>Efird, Jimmy T., PhD, MS</creator><creator>O'Neal, Wesley T., MD</creator><creator>O'Neal, Jason B., MD</creator><creator>Ferguson, T. Bruce, MD</creator><creator>Chitwood, W. Randolph, MD</creator><creator>Kypson, Alan P., MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130701</creationdate><title>Effect of Peripheral Arterial Disease and Race on Survival After Coronary Artery Bypass Grafting</title><author>Efird, Jimmy T., PhD, MS ; O'Neal, Wesley T., MD ; O'Neal, Jason B., MD ; Ferguson, T. Bruce, MD ; Chitwood, W. Randolph, MD ; Kypson, Alan P., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c495t-2c2cb44b717ceac26f87cd948502b6040f905851db30adf5c8f5bcb1b9a2a0163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Angiography</topic><topic>Ankle Brachial Index</topic><topic>Cardiothoracic Surgery</topic><topic>Confidence Intervals</topic><topic>Continental Population Groups</topic><topic>Coronary Artery Bypass - mortality</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - ethnology</topic><topic>Coronary Artery Disease - surgery</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Incidence</topic><topic>North Carolina - epidemiology</topic><topic>Peripheral Arterial Disease - complications</topic><topic>Peripheral Arterial Disease - diagnosis</topic><topic>Peripheral Arterial Disease - ethnology</topic><topic>Postoperative Period</topic><topic>Proportional Hazards Models</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Surgery</topic><topic>Survival Rate - trends</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Efird, Jimmy T., PhD, MS</creatorcontrib><creatorcontrib>O'Neal, Wesley T., MD</creatorcontrib><creatorcontrib>O'Neal, Jason B., MD</creatorcontrib><creatorcontrib>Ferguson, T. Bruce, MD</creatorcontrib><creatorcontrib>Chitwood, W. Randolph, MD</creatorcontrib><creatorcontrib>Kypson, Alan P., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Efird, Jimmy T., PhD, MS</au><au>O'Neal, Wesley T., MD</au><au>O'Neal, Jason B., MD</au><au>Ferguson, T. Bruce, MD</au><au>Chitwood, W. Randolph, MD</au><au>Kypson, Alan P., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Peripheral Arterial Disease and Race on Survival After Coronary Artery Bypass Grafting</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2013-07-01</date><risdate>2013</risdate><volume>96</volume><issue>1</issue><spage>112</spage><epage>118</epage><pages>112-118</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Background Although peripheral arterial disease (PAD) is more prevalent among blacks, the effect of race on long-term survival after coronary artery bypass grafting (CABG) has not been examined in this population. Methods A retrospective cohort study was conducted of CABG patients between 1992 and 2011. Long-term survival was compared in patients with and without PAD and stratified by race. Hazard ratios (HR) and 95% confidence intervals were computed using a Cox regression model. Results Of 13,053 patients who underwent CABG, 1,501 (11%) had PAD, comprising 311 blacks and 1,190 whites. Median follow-up was 8.3 years. Long-term survival differed by race (no PAD: HR, 1.0; white PAD: adjusted HR, 1.5, 95% confidence interval, 1.4 to 1.6; black PAD: adjusted HR, 2.1, 95% confidence interval, 1.8 to 2.5; p < 0.0001 for trend). Conclusions Risk of death after CABG was comparatively higher among black PAD patients. This finding provides useful outcome information for surgeons and their patients.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>23735717</pmid><doi>10.1016/j.athoracsur.2013.04.006</doi><tpages>7</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Angiography Ankle Brachial Index Cardiothoracic Surgery Confidence Intervals Continental Population Groups Coronary Artery Bypass - mortality Coronary Artery Disease - complications Coronary Artery Disease - ethnology Coronary Artery Disease - surgery Follow-Up Studies Humans Incidence North Carolina - epidemiology Peripheral Arterial Disease - complications Peripheral Arterial Disease - diagnosis Peripheral Arterial Disease - ethnology Postoperative Period Proportional Hazards Models Retrospective Studies Risk Factors Surgery Survival Rate - trends Time Factors Treatment Outcome |
| title | Effect of Peripheral Arterial Disease and Race on Survival After Coronary Artery Bypass Grafting |
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