Nephrotoxicity of bromobenzene in mice

I.p. administration of bromobenzene to male mice at doses ranging from 0 to 9.4 mmol kg resulted in a dose-dependent increase in blood urea nitrogen (BUN) and serum glutamic-pyruvic transaminase (SGPT) activity and a decrease in renal cortical accumulation of para-aminohippurate (PAH) and tetraethyl...

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Veröffentlicht in:	Toxicology letters 1984, Vol.20 (1), p.23-32
Hauptverfasser:	Rush, Glenn F., Kuo, Chao-Hen, Hook, Jerry B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzoflavones - pharmacology beta-Naphthoflavone Biological and medical sciences Bromobenzene Bromobenzenes - metabolism Bromobenzenes - toxicity bromocatechol bromophenol Chemical and industrial products toxicology. Toxic occupational diseases Kidney - drug effects Liver - drug effects Male Maleates - pharmacology Medical sciences Mice Mice, Inbred ICR nephrotoxicity Sulfhydryl Compounds - analysis Toxicology Various organic compounds
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