Combined use of biochemical indicators to assess sublethal pollution effects on the Gulf Killifish (Fundulus grandis)
Total cytochrome P-450 content, aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) activities, and the specific induction of the LM4b isozyme of the cytochrome P-450 system were measured in the livers of gulf killifish from the heavily polluted Bayou Chico. Similar determinat...
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Veröffentlicht in: | Archives of environmental contamination and toxicology 1988-07, Vol.17 (4), p.437-441 |
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container_title | Archives of environmental contamination and toxicology |
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creator | SCHOOR, W. P WILLIAMS, D. E LECH, J. J |
description | Total cytochrome P-450 content, aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) activities, and the specific induction of the LM4b isozyme of the cytochrome P-450 system were measured in the livers of gulf killifish from the heavily polluted Bayou Chico. Similar determinations were carried out on variously treated fish (uninjected, of pretreated with 3-methylcholanthrene (3MC), phenylbarbital (PB) or corn oil) from the unpolluted Santa Rosa Sound. EROD, AHH and LM4b were induced in the 3MC-treated fish and, to a lesser extent, in fish from the Bayou Chico. This was consistent with the reported presence of PAHs in Bayou Chico, and demonstrated the utility of biochemical indicators in determining sublethal pollution effects in gulf killifish. |
doi_str_mv | 10.1007/BF01055508 |
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This was consistent with the reported presence of PAHs in Bayou Chico, and demonstrated the utility of biochemical indicators in determining sublethal pollution effects in gulf killifish.</description><identifier>ISSN: 0090-4341</identifier><identifier>EISSN: 1432-0703</identifier><identifier>DOI: 10.1007/BF01055508</identifier><identifier>PMID: 3408266</identifier><identifier>CODEN: AECTCV</identifier><language>eng</language><publisher>Heidelberg: Springer-Verlag</publisher><subject>Animals ; Biological and medical sciences ; Cyprinodontiformes - physiology ; Environmental pollutants toxicology ; Killifishes - physiology ; Liver - drug effects ; Liver - enzymology ; Medical sciences ; Toxicology ; Water ; Water Pollutants - toxicity ; Water Pollutants, Chemical - toxicity</subject><ispartof>Archives of environmental contamination and toxicology, 1988-07, Vol.17 (4), p.437-441</ispartof><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c342t-7b1def2bc30c494639ea40eb00623152f48745ce527555c24ff32890c7f6f45a3</citedby><cites>FETCH-LOGICAL-c342t-7b1def2bc30c494639ea40eb00623152f48745ce527555c24ff32890c7f6f45a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7104085$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3408266$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SCHOOR, W. P</creatorcontrib><creatorcontrib>WILLIAMS, D. E</creatorcontrib><creatorcontrib>LECH, J. J</creatorcontrib><title>Combined use of biochemical indicators to assess sublethal pollution effects on the Gulf Killifish (Fundulus grandis)</title><title>Archives of environmental contamination and toxicology</title><addtitle>Arch Environ Contam Toxicol</addtitle><description>Total cytochrome P-450 content, aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) activities, and the specific induction of the LM4b isozyme of the cytochrome P-450 system were measured in the livers of gulf killifish from the heavily polluted Bayou Chico. Similar determinations were carried out on variously treated fish (uninjected, of pretreated with 3-methylcholanthrene (3MC), phenylbarbital (PB) or corn oil) from the unpolluted Santa Rosa Sound. EROD, AHH and LM4b were induced in the 3MC-treated fish and, to a lesser extent, in fish from the Bayou Chico. This was consistent with the reported presence of PAHs in Bayou Chico, and demonstrated the utility of biochemical indicators in determining sublethal pollution effects in gulf killifish.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cyprinodontiformes - physiology</subject><subject>Environmental pollutants toxicology</subject><subject>Killifishes - physiology</subject><subject>Liver - drug effects</subject><subject>Liver - enzymology</subject><subject>Medical sciences</subject><subject>Toxicology</subject><subject>Water</subject><subject>Water Pollutants - toxicity</subject><subject>Water Pollutants, Chemical - toxicity</subject><issn>0090-4341</issn><issn>1432-0703</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLJDEUhYM4aPvYuBeyENGB0ptHPXrpNNM6jOBG10UqdWNHUpW2bmXhvzeDjbM6F87HgfsxdibgRgDUt7_WIKAsS2j22EJoJQuoQe2zBcASCq20OGRHRG8AQjaNPmAHSkMjq2rB0ioOnR-x54mQR8c7H-0GB29N4H7sc85xIj5HboiQiFPqAs6bXG9jCGn2ceToHNqZeD7nDfL7FBz_60PwztOGX63T2KeQiL9OJk_S9Qn74UwgPN3lMXtZ_35ePRSPT_d_VnePhVVazkXdiR6d7KwCq5e6Uks0GrADqKQSpXS6qXVpsZR1_t5K7ZySzRJs7SqnS6OO2eXX7naK7wlpbgdPFkMwI8ZErVB1pUXTZPDnF2inSDSha7eTH8z00Qpo_zlu_zvO8PluNXUD9t_oTmruL3a9oazR5aetp2-sFpDBUn0CRueDcA</recordid><startdate>19880701</startdate><enddate>19880701</enddate><creator>SCHOOR, W. 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subjects | Animals Biological and medical sciences Cyprinodontiformes - physiology Environmental pollutants toxicology Killifishes - physiology Liver - drug effects Liver - enzymology Medical sciences Toxicology Water Water Pollutants - toxicity Water Pollutants, Chemical - toxicity |
title | Combined use of biochemical indicators to assess sublethal pollution effects on the Gulf Killifish (Fundulus grandis) |
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