Combined use of biochemical indicators to assess sublethal pollution effects on the Gulf Killifish (Fundulus grandis)

Total cytochrome P-450 content, aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) activities, and the specific induction of the LM4b isozyme of the cytochrome P-450 system were measured in the livers of gulf killifish from the heavily polluted Bayou Chico. Similar determinat...

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Veröffentlicht in:Archives of environmental contamination and toxicology 1988-07, Vol.17 (4), p.437-441
Hauptverfasser: SCHOOR, W. P, WILLIAMS, D. E, LECH, J. J
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container_title Archives of environmental contamination and toxicology
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creator SCHOOR, W. P
WILLIAMS, D. E
LECH, J. J
description Total cytochrome P-450 content, aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin O-deethylase (EROD) activities, and the specific induction of the LM4b isozyme of the cytochrome P-450 system were measured in the livers of gulf killifish from the heavily polluted Bayou Chico. Similar determinations were carried out on variously treated fish (uninjected, of pretreated with 3-methylcholanthrene (3MC), phenylbarbital (PB) or corn oil) from the unpolluted Santa Rosa Sound. EROD, AHH and LM4b were induced in the 3MC-treated fish and, to a lesser extent, in fish from the Bayou Chico. This was consistent with the reported presence of PAHs in Bayou Chico, and demonstrated the utility of biochemical indicators in determining sublethal pollution effects in gulf killifish.
doi_str_mv 10.1007/BF01055508
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Animals
Biological and medical sciences
Cyprinodontiformes - physiology
Environmental pollutants toxicology
Killifishes - physiology
Liver - drug effects
Liver - enzymology
Medical sciences
Toxicology
Water
Water Pollutants - toxicity
Water Pollutants, Chemical - toxicity
title Combined use of biochemical indicators to assess sublethal pollution effects on the Gulf Killifish (Fundulus grandis)
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