Three new nickel enzymes from anaerobic bacteria
Until recently nickel was not considered to be an element of biological importance. Nutritional studies have shown, however, that many eucaryotic and procaryotic organism are dependent on the transition metal for growth. Four enzymes are presently known to contain nickel: urease from plant and from...
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Veröffentlicht in: | Die Naturwissenschaften 1983-01, Vol.70 (2), p.60-64 |
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creator | Thauer, R K Brandis-Heep, A Diekert, G Gilles, H-H Graf, E G Jaenchen, R Schoenheit, P |
description | Until recently nickel was not considered to be an element of biological importance. Nutritional studies have shown, however, that many eucaryotic and procaryotic organism are dependent on the transition metal for growth. Four enzymes are presently known to contain nickel: urease from plant and from bacteria; methyl CoM reductase from methanogenic bacteria; all "uptake" hydrogenases investigated so far; and carbon monoxide dehydrogenase from anaerobic bacteria. The prosthetic group of the methyl CoM reductase has been identified as a nickel tetrapyrrole, the structure of which has been elucidated. |
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Nutritional studies have shown, however, that many eucaryotic and procaryotic organism are dependent on the transition metal for growth. Four enzymes are presently known to contain nickel: urease from plant and from bacteria; methyl CoM reductase from methanogenic bacteria; all "uptake" hydrogenases investigated so far; and carbon monoxide dehydrogenase from anaerobic bacteria. 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title | Three new nickel enzymes from anaerobic bacteria |
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