Clinical course, complication rate and outcome of segmental resection and distraction osteogenesis after chronic tibial osteitis

Abstract Introduction Radical segmental resection and subsequent distraction osteogenesis are considered the gold standard in the treatment of chronic tibial osteitis. We investigated the clinical course of treatment, particularly with respect to patients’ quality of life, and the complication rate...

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Veröffentlicht in:Injury 2013-08, Vol.44 (8), p.1049-1056
Hauptverfasser: Spiegl, Ulrich, Pätzold, Robert, Friederichs, Jan, Hungerer, Sven, Militz, Matthias, Bühren, Volker
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container_end_page 1056
container_issue 8
container_start_page 1049
container_title Injury
container_volume 44
creator Spiegl, Ulrich
Pätzold, Robert
Friederichs, Jan
Hungerer, Sven
Militz, Matthias
Bühren, Volker
description Abstract Introduction Radical segmental resection and subsequent distraction osteogenesis are considered the gold standard in the treatment of chronic tibial osteitis. We investigated the clinical course of treatment, particularly with respect to patients’ quality of life, and the complication rate associated with this technique. Methods In this prospective case series, 25 patients (22 men, 3 women, average age: 46 years) with chronic post-traumatic tibial osteitis were managed operatively from 2006 to 2009. Standardised treatment included bacterial eradication by segmental resection, bone transport using Ilizarov apparatus, and docking manoeuvre. The follow-up rates during bacterial eradication, bone transport, post docking, and complete osseous consolidation were 100% while follow-up two years after completed consolidation was 76%. The main outcome measurements consisted of the quality of life (Medical Outcomes Study 36-Item Short Form Health Survey (SF-36 score)) and the virtual analogue scale (VAS) of pain during the five stages of therapy. Additionally, all complications and difficulties were documented. Results The average defect size was 5.3 cm (range: 3–13). The healing index was 57 days per cm transport (range: 18–172). The overall treatment time averaged 93 weeks (range: 38–183). Patients suffered 22 minor and 13 major complications including one amputation. The average complication rate per patient consisted of 0.88 minor and 0.52 major complications. After the period of bone transport, the physical and mental component summary scores increased continuously. After completed consolidation, the average mental summary score was comparable to a normal collective. Conclusions Distraction osteogenesis is challenging for both the patient and the surgeon. The arduous and demanding nature of the clinical course subjects the patient to considerable mental and physical stress. Thankfully, the average physical and mental status of health continues to improve during the clinical course of treatment. The 2-year success rate of the distraction osteogenesis in an infected tibia is 96%.
doi_str_mv 10.1016/j.injury.2013.05.003
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We investigated the clinical course of treatment, particularly with respect to patients’ quality of life, and the complication rate associated with this technique. Methods In this prospective case series, 25 patients (22 men, 3 women, average age: 46 years) with chronic post-traumatic tibial osteitis were managed operatively from 2006 to 2009. Standardised treatment included bacterial eradication by segmental resection, bone transport using Ilizarov apparatus, and docking manoeuvre. The follow-up rates during bacterial eradication, bone transport, post docking, and complete osseous consolidation were 100% while follow-up two years after completed consolidation was 76%. The main outcome measurements consisted of the quality of life (Medical Outcomes Study 36-Item Short Form Health Survey (SF-36 score)) and the virtual analogue scale (VAS) of pain during the five stages of therapy. Additionally, all complications and difficulties were documented. Results The average defect size was 5.3 cm (range: 3–13). The healing index was 57 days per cm transport (range: 18–172). The overall treatment time averaged 93 weeks (range: 38–183). Patients suffered 22 minor and 13 major complications including one amputation. The average complication rate per patient consisted of 0.88 minor and 0.52 major complications. After the period of bone transport, the physical and mental component summary scores increased continuously. After completed consolidation, the average mental summary score was comparable to a normal collective. Conclusions Distraction osteogenesis is challenging for both the patient and the surgeon. The arduous and demanding nature of the clinical course subjects the patient to considerable mental and physical stress. Thankfully, the average physical and mental status of health continues to improve during the clinical course of treatment. The 2-year success rate of the distraction osteogenesis in an infected tibia is 96%.</description><identifier>ISSN: 0020-1383</identifier><identifier>EISSN: 1879-0267</identifier><identifier>DOI: 10.1016/j.injury.2013.05.003</identifier><identifier>PMID: 23747125</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Adult ; Bacterial eradication ; Chronic tibial osteitis ; Distraction osteogenesis ; External Fixators - adverse effects ; Female ; Humans ; Ilizarov fixator ; Ilizarov Technique ; Male ; Middle Aged ; Orthopedics ; Osteitis - complications ; Osteitis - psychology ; Osteitis - surgery ; Osteogenesis, Distraction - instrumentation ; Osteogenesis, Distraction - methods ; Quality of Life ; Reconstructive Surgical Procedures - methods ; Segmental resection ; SF 36 ; Tibial Fractures - complications ; Tibial Fractures - surgery ; Treatment Outcome ; Young Adult</subject><ispartof>Injury, 2013-08, Vol.44 (8), p.1049-1056</ispartof><rights>Elsevier Ltd</rights><rights>2013 Elsevier Ltd</rights><rights>Copyright © 2013 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-b0edbe3605efa4dd51ab752d0c189a6eb312708d47f1705ec9bd634270cab8113</citedby><cites>FETCH-LOGICAL-c483t-b0edbe3605efa4dd51ab752d0c189a6eb312708d47f1705ec9bd634270cab8113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0020138313002313$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23747125$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spiegl, Ulrich</creatorcontrib><creatorcontrib>Pätzold, Robert</creatorcontrib><creatorcontrib>Friederichs, Jan</creatorcontrib><creatorcontrib>Hungerer, Sven</creatorcontrib><creatorcontrib>Militz, Matthias</creatorcontrib><creatorcontrib>Bühren, Volker</creatorcontrib><title>Clinical course, complication rate and outcome of segmental resection and distraction osteogenesis after chronic tibial osteitis</title><title>Injury</title><addtitle>Injury</addtitle><description>Abstract Introduction Radical segmental resection and subsequent distraction osteogenesis are considered the gold standard in the treatment of chronic tibial osteitis. We investigated the clinical course of treatment, particularly with respect to patients’ quality of life, and the complication rate associated with this technique. Methods In this prospective case series, 25 patients (22 men, 3 women, average age: 46 years) with chronic post-traumatic tibial osteitis were managed operatively from 2006 to 2009. Standardised treatment included bacterial eradication by segmental resection, bone transport using Ilizarov apparatus, and docking manoeuvre. The follow-up rates during bacterial eradication, bone transport, post docking, and complete osseous consolidation were 100% while follow-up two years after completed consolidation was 76%. The main outcome measurements consisted of the quality of life (Medical Outcomes Study 36-Item Short Form Health Survey (SF-36 score)) and the virtual analogue scale (VAS) of pain during the five stages of therapy. Additionally, all complications and difficulties were documented. Results The average defect size was 5.3 cm (range: 3–13). The healing index was 57 days per cm transport (range: 18–172). The overall treatment time averaged 93 weeks (range: 38–183). Patients suffered 22 minor and 13 major complications including one amputation. The average complication rate per patient consisted of 0.88 minor and 0.52 major complications. After the period of bone transport, the physical and mental component summary scores increased continuously. After completed consolidation, the average mental summary score was comparable to a normal collective. Conclusions Distraction osteogenesis is challenging for both the patient and the surgeon. The arduous and demanding nature of the clinical course subjects the patient to considerable mental and physical stress. Thankfully, the average physical and mental status of health continues to improve during the clinical course of treatment. The 2-year success rate of the distraction osteogenesis in an infected tibia is 96%.</description><subject>Adult</subject><subject>Bacterial eradication</subject><subject>Chronic tibial osteitis</subject><subject>Distraction osteogenesis</subject><subject>External Fixators - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Ilizarov fixator</subject><subject>Ilizarov Technique</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Orthopedics</subject><subject>Osteitis - complications</subject><subject>Osteitis - psychology</subject><subject>Osteitis - surgery</subject><subject>Osteogenesis, Distraction - instrumentation</subject><subject>Osteogenesis, Distraction - methods</subject><subject>Quality of Life</subject><subject>Reconstructive Surgical Procedures - methods</subject><subject>Segmental resection</subject><subject>SF 36</subject><subject>Tibial Fractures - complications</subject><subject>Tibial Fractures - surgery</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>0020-1383</issn><issn>1879-0267</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUcFu1DAQtRCIbgt_gFCOHEgYx0mcvSChFVCkSj20nC3HnhSHJF48DtLe-HQcsnDg0ovHHr83T_MeY684FBx4824o3Dws4VSUwEUBdQEgnrAdb-U-h7KRT9kOoISci1ZcsEuiAYBLEOI5uyiFrCQv6x37dRjd7IweM-OXQPg21ek4pk50fs6Cjpjp2WZ-iekDM99nhA8TzjFRAhKaP7gVYh3FoLe3p4j-AWckR5nuI4bMfAs-KWXRdS5xV4SLjl6wZ70eCV-e6xX7-unj_eE6v7n9_OXw4SY3VSti3gHaDkUDNfa6srbmupN1acHwdq8b7AQvJbS2kn1askaz72wjqtQzums5F1fszTb3GPyPBSmqyZHBcdQz-oUUF1JUYt_UdYJWG9QETxSwV8fgJh1OioNavVeD2rxXq_cKapW8T7TXZ4Wlm9D-I_01OwHebwBMe_50GBQZh7NB60LyUVnvHlP4f4A5p_cdT0hDSnBOHiquqFSg7tb81_i5SLd0it-W669V</recordid><startdate>20130801</startdate><enddate>20130801</enddate><creator>Spiegl, Ulrich</creator><creator>Pätzold, Robert</creator><creator>Friederichs, Jan</creator><creator>Hungerer, Sven</creator><creator>Militz, Matthias</creator><creator>Bühren, Volker</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130801</creationdate><title>Clinical course, complication rate and outcome of segmental resection and distraction osteogenesis after chronic tibial osteitis</title><author>Spiegl, Ulrich ; Pätzold, Robert ; Friederichs, Jan ; Hungerer, Sven ; Militz, Matthias ; Bühren, Volker</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-b0edbe3605efa4dd51ab752d0c189a6eb312708d47f1705ec9bd634270cab8113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Bacterial eradication</topic><topic>Chronic tibial osteitis</topic><topic>Distraction osteogenesis</topic><topic>External Fixators - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Ilizarov fixator</topic><topic>Ilizarov Technique</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Orthopedics</topic><topic>Osteitis - complications</topic><topic>Osteitis - psychology</topic><topic>Osteitis - surgery</topic><topic>Osteogenesis, Distraction - instrumentation</topic><topic>Osteogenesis, Distraction - methods</topic><topic>Quality of Life</topic><topic>Reconstructive Surgical Procedures - methods</topic><topic>Segmental resection</topic><topic>SF 36</topic><topic>Tibial Fractures - complications</topic><topic>Tibial Fractures - surgery</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spiegl, Ulrich</creatorcontrib><creatorcontrib>Pätzold, Robert</creatorcontrib><creatorcontrib>Friederichs, Jan</creatorcontrib><creatorcontrib>Hungerer, Sven</creatorcontrib><creatorcontrib>Militz, Matthias</creatorcontrib><creatorcontrib>Bühren, Volker</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Injury</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spiegl, Ulrich</au><au>Pätzold, Robert</au><au>Friederichs, Jan</au><au>Hungerer, Sven</au><au>Militz, Matthias</au><au>Bühren, Volker</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical course, complication rate and outcome of segmental resection and distraction osteogenesis after chronic tibial osteitis</atitle><jtitle>Injury</jtitle><addtitle>Injury</addtitle><date>2013-08-01</date><risdate>2013</risdate><volume>44</volume><issue>8</issue><spage>1049</spage><epage>1056</epage><pages>1049-1056</pages><issn>0020-1383</issn><eissn>1879-0267</eissn><abstract>Abstract Introduction Radical segmental resection and subsequent distraction osteogenesis are considered the gold standard in the treatment of chronic tibial osteitis. We investigated the clinical course of treatment, particularly with respect to patients’ quality of life, and the complication rate associated with this technique. Methods In this prospective case series, 25 patients (22 men, 3 women, average age: 46 years) with chronic post-traumatic tibial osteitis were managed operatively from 2006 to 2009. Standardised treatment included bacterial eradication by segmental resection, bone transport using Ilizarov apparatus, and docking manoeuvre. The follow-up rates during bacterial eradication, bone transport, post docking, and complete osseous consolidation were 100% while follow-up two years after completed consolidation was 76%. The main outcome measurements consisted of the quality of life (Medical Outcomes Study 36-Item Short Form Health Survey (SF-36 score)) and the virtual analogue scale (VAS) of pain during the five stages of therapy. Additionally, all complications and difficulties were documented. Results The average defect size was 5.3 cm (range: 3–13). The healing index was 57 days per cm transport (range: 18–172). The overall treatment time averaged 93 weeks (range: 38–183). Patients suffered 22 minor and 13 major complications including one amputation. The average complication rate per patient consisted of 0.88 minor and 0.52 major complications. After the period of bone transport, the physical and mental component summary scores increased continuously. After completed consolidation, the average mental summary score was comparable to a normal collective. Conclusions Distraction osteogenesis is challenging for both the patient and the surgeon. The arduous and demanding nature of the clinical course subjects the patient to considerable mental and physical stress. Thankfully, the average physical and mental status of health continues to improve during the clinical course of treatment. The 2-year success rate of the distraction osteogenesis in an infected tibia is 96%.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>23747125</pmid><doi>10.1016/j.injury.2013.05.003</doi><tpages>8</tpages></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Adult
Bacterial eradication
Chronic tibial osteitis
Distraction osteogenesis
External Fixators - adverse effects
Female
Humans
Ilizarov fixator
Ilizarov Technique
Male
Middle Aged
Orthopedics
Osteitis - complications
Osteitis - psychology
Osteitis - surgery
Osteogenesis, Distraction - instrumentation
Osteogenesis, Distraction - methods
Quality of Life
Reconstructive Surgical Procedures - methods
Segmental resection
SF 36
Tibial Fractures - complications
Tibial Fractures - surgery
Treatment Outcome
Young Adult
title Clinical course, complication rate and outcome of segmental resection and distraction osteogenesis after chronic tibial osteitis
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