Photoacoustic imaging of the bladder: a pilot study
Photoacoustic imaging is a promising new technology that combines tissue optical characteristics with ultrasound transmission and can potentially visualize tumor depth in bladder cancer. We imaged simulated tumors in 5 fresh porcine bladders with conventional pulse-echo sonography and photoacoustic...
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Veröffentlicht in: | Journal of ultrasound in medicine 2013-07, Vol.32 (7), p.1245-1250 |
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creator | Kamaya, Aya Vaithilingam, Srikant Chung, Benjamin I Oralkan, Omer Khuri-Yakub, Butrus T |
description | Photoacoustic imaging is a promising new technology that combines tissue optical characteristics with ultrasound transmission and can potentially visualize tumor depth in bladder cancer. We imaged simulated tumors in 5 fresh porcine bladders with conventional pulse-echo sonography and photoacoustic imaging. Isoechoic biomaterials of different optical qualities were used. In all 5 of the bladder specimens, photoacoustic imaging showed injected biomaterials, containing varying degrees of pigment, better than control pulse-echo sonography. Photoacoustic imaging may be complementary to diagnostic information obtained by cystoscopy and urine cytologic analysis and could potentially obviate the need for biopsy in some tumors before definitive treatment. |
doi_str_mv | 10.7863/ultra.32.7.1245 |
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We imaged simulated tumors in 5 fresh porcine bladders with conventional pulse-echo sonography and photoacoustic imaging. Isoechoic biomaterials of different optical qualities were used. In all 5 of the bladder specimens, photoacoustic imaging showed injected biomaterials, containing varying degrees of pigment, better than control pulse-echo sonography. Photoacoustic imaging may be complementary to diagnostic information obtained by cystoscopy and urine cytologic analysis and could potentially obviate the need for biopsy in some tumors before definitive treatment.</description><subject>Algorithms</subject><subject>Animals</subject><subject>Elasticity Imaging Techniques - instrumentation</subject><subject>Elasticity Imaging Techniques - methods</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Image Enhancement - instrumentation</subject><subject>Image Enhancement - methods</subject><subject>Image Interpretation, Computer-Assisted - instrumentation</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>In Vitro Techniques</subject><subject>Phantoms, Imaging</subject><subject>Photoacoustic Techniques - instrumentation</subject><subject>Photoacoustic Techniques - methods</subject><subject>Pilot Projects</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Swine</subject><subject>Urinary Bladder - diagnostic imaging</subject><subject>Urinary Bladder Neoplasms - diagnostic imaging</subject><issn>0278-4297</issn><issn>1550-9613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDtPwzAUhS0EoqUws6GMLEnt6zi22RDiJVWCAWbLr7RBaV1sZ-i_J6WF6S7fPTrnQ-ia4IqLhs6HPkddUah4RaBmJ2hKGMOlbAg9RVMMXJQ1SD5BFyl9YQyY8PocTYAKXNOaTxF9X4UctA1Dyp0turVedptlEdoir3xheu2cj3eFLrZdH3KR8uB2l-is1X3yV8c7Q59Pjx8PL-Xi7fn14X5RWmAkl2C1cFiCBC04s5IY0YCRmFCGMWtrSppWMgfa2sY4J4AbA63F3jrvJACdodtD7jaG78GnrNZdsr7v9caPfRWhHBrJucQjOj-gNoaUom_VNo5b4k4RrPam1K8pRUFxtTc1ftwcwwez9u6f_1NDfwD072Rk</recordid><startdate>201307</startdate><enddate>201307</enddate><creator>Kamaya, Aya</creator><creator>Vaithilingam, Srikant</creator><creator>Chung, Benjamin I</creator><creator>Oralkan, Omer</creator><creator>Khuri-Yakub, Butrus T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201307</creationdate><title>Photoacoustic imaging of the bladder: a pilot study</title><author>Kamaya, Aya ; 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We imaged simulated tumors in 5 fresh porcine bladders with conventional pulse-echo sonography and photoacoustic imaging. Isoechoic biomaterials of different optical qualities were used. In all 5 of the bladder specimens, photoacoustic imaging showed injected biomaterials, containing varying degrees of pigment, better than control pulse-echo sonography. Photoacoustic imaging may be complementary to diagnostic information obtained by cystoscopy and urine cytologic analysis and could potentially obviate the need for biopsy in some tumors before definitive treatment.</abstract><cop>England</cop><pmid>23804347</pmid><doi>10.7863/ultra.32.7.1245</doi><tpages>6</tpages></addata></record> |
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subjects | Algorithms Animals Elasticity Imaging Techniques - instrumentation Elasticity Imaging Techniques - methods Equipment Design Equipment Failure Analysis Image Enhancement - instrumentation Image Enhancement - methods Image Interpretation, Computer-Assisted - instrumentation Image Interpretation, Computer-Assisted - methods In Vitro Techniques Phantoms, Imaging Photoacoustic Techniques - instrumentation Photoacoustic Techniques - methods Pilot Projects Reproducibility of Results Sensitivity and Specificity Swine Urinary Bladder - diagnostic imaging Urinary Bladder Neoplasms - diagnostic imaging |
title | Photoacoustic imaging of the bladder: a pilot study |
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