Anti-vascular endothelial growth factor therapy in the era of personalized medicine

Purpose To review the role of anti-vascular endothelial growth factor (anti-VEGF) therapies in the personalized medicine era. Methods We searched PubMed for prospective clinical trials published through October 2012 of anti-VEGF agents approved by the U.S. Food and Drug Administration or the Europea...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 2013-07, Vol.72 (1), p.1-12
Hauptverfasser:	Féliz, Luis R., Tsimberidou, Apostolia M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - administration & dosage Angiogenesis Inhibitors - adverse effects Angiogenesis Inhibitors - therapeutic use Animals Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Cancer Research Humans Medical sciences Medicine Medicine & Public Health Molecular Targeted Therapy - adverse effects Neoplasm Proteins - antagonists & inhibitors Neoplasm Proteins - metabolism Neoplasms - blood supply Neoplasms - drug therapy Neoplasms - metabolism Neovascularization, Pathologic - prevention & control Oncology Pharmacology. Drug treatments Pharmacology/Toxicology Precision medicine Precision Medicine - trends Protein Kinase Inhibitors - administration & dosage Protein Kinase Inhibitors - adverse effects Protein Kinase Inhibitors - therapeutic use Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors Receptors, Vascular Endothelial Growth Factor - metabolism Review Article Signal Transduction - drug effects Vascular Endothelial Growth Factors - antagonists & inhibitors Vascular Endothelial Growth Factors - metabolism
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