Bilateral Wilms Tumor and Early Presentation in Pediatric Patients Is Associated with the Truncation of the Wilms Tumor 1 Protein

Objectives To investigate the frequency of constitutional Wilms tumor 1 gene ( WT1 ) abnormalities in children with bilateral Wilms tumor (WT) and the age of tumor onset in patients with a mutation. Study design Eight patients with bilateral WT were studied. High-resolution melting and direct sequen...

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