Analysis of the beta-globin gene in DNA of suspected thalassemic great apes

DNA was recovered from teeth of 2 great ape skeletons, Pan troglodytes (Ptr) and Pongo pygmaeus (Ppy), belonging to a 19th-century zoological collection. The skeletons presented morphological alterations possibly associated with β-thalassemia: Ptr had deformation of the calvaria and oro-maxillo-faci...

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Veröffentlicht in:	Genetics and molecular research 2013-05, Vol.12 (2), p.1731-1739
Hauptverfasser:	Vuch, J, Siori, M S, Bigatti, M P, Segat, L, De Fabrizio, G, Crovella, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence beta-Globins - chemistry beta-Globins - genetics beta-Thalassemia - genetics Bone and Bones - pathology DNA - genetics Electrophoresis, Agar Gel Exons - genetics Humans Likelihood Functions Molecular Sequence Data Pan troglodytes Pan troglodytes - genetics Phylogeny Pongo pygmaeus Pongo pygmaeus - genetics Sequence Alignment Skull - pathology
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